Gene description for LRRN4CL
Gene name LRRN4 C-terminal like
Gene symbol LRRN4CL
Other names/aliases -
Species Homo sapiens
 Database cross references - LRRN4CL
ExoCarta ExoCarta_221091
Vesiclepedia VP_221091
Entrez Gene 221091
HGNC 33724
UniProt Q8ND94  
 LRRN4CL identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for LRRN4CL
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified LRRN4CL in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for LRRN4CL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
2 IMMT 10989
Affinity Capture-MS Homo sapiens
3 SGPL1 8879
Affinity Capture-MS Homo sapiens
4 HEATR6  
Affinity Capture-MS Homo sapiens
5 LRFN1  
Affinity Capture-MS Homo sapiens
6 PIGG  
Affinity Capture-MS Homo sapiens
7 CDS2 8760
Affinity Capture-MS Homo sapiens
8 CTNNA2 1496
Affinity Capture-MS Homo sapiens
9 MAP2K2 5605
Affinity Capture-MS Homo sapiens
10 WDR11 55717
Affinity Capture-MS Homo sapiens
11 SEC61A2 55176
Affinity Capture-MS Homo sapiens
12 SLC25A6 293
Affinity Capture-MS Homo sapiens
13 MBOAT7 79143
Affinity Capture-MS Homo sapiens
14 OCLN 100506658
Affinity Capture-MS Homo sapiens
15 MYCBP2 23077
Affinity Capture-MS Homo sapiens
16 FASTKD1  
Affinity Capture-MS Homo sapiens
17 BTAF1 9044
Affinity Capture-MS Homo sapiens
18 ATP1A3 478
Affinity Capture-MS Homo sapiens
19 CTPS2 56474
Affinity Capture-MS Homo sapiens
20 SRPK2 6733
Biochemical Activity Homo sapiens
21 MTX2 10651
Affinity Capture-MS Homo sapiens
22 CADM4 199731
Affinity Capture-MS Homo sapiens
23 SLCO4A1 28231
Affinity Capture-MS Homo sapiens
24 SEZ6L2 26470
Affinity Capture-MS Homo sapiens
25 CLPTM1 1209
Affinity Capture-MS Homo sapiens
26 HSPA13 6782
Affinity Capture-MS Homo sapiens
27 ATP12A 479
Affinity Capture-MS Homo sapiens
28 SRPR 6734
Affinity Capture-MS Homo sapiens
29 SAMM50 25813
Affinity Capture-MS Homo sapiens
30 GLS 2744
Affinity Capture-MS Homo sapiens
31 SLC25A15  
Affinity Capture-MS Homo sapiens
32 C17orf75 64149
Affinity Capture-MS Homo sapiens
33 SGPP1 81537
Affinity Capture-MS Homo sapiens
34 PODXL2 50512
Affinity Capture-MS Homo sapiens
35 PCDH1 5097
Affinity Capture-MS Homo sapiens
36 ERGIC1 57222
Affinity Capture-MS Homo sapiens
37 GHITM 27069
Affinity Capture-MS Homo sapiens
38 ARL8B 55207
Affinity Capture-MS Homo sapiens
39 TUBA1A 7846
Affinity Capture-MS Homo sapiens
40 TM9SF3 56889
Affinity Capture-MS Homo sapiens
41 AUP1 550
Affinity Capture-MS Homo sapiens
42 SOAT1 6646
Affinity Capture-MS Homo sapiens
43 ITFG1 81533
Affinity Capture-MS Homo sapiens
44 SLC25A4 291
Affinity Capture-MS Homo sapiens
45 LPGAT1 9926
Affinity Capture-MS Homo sapiens
46 GLT8D1 55830
Affinity Capture-MS Homo sapiens
47 FAM115C  
Affinity Capture-MS Homo sapiens
48 SPRYD3 84926
Affinity Capture-MS Homo sapiens
49 SLC39A11  
Affinity Capture-MS Homo sapiens
50 AGPAT6 137964
Affinity Capture-MS Homo sapiens
51 CHCHD6 84303
Affinity Capture-MS Homo sapiens
52 ORC4  
Affinity Capture-MS Homo sapiens
53 SFXN3 81855
Affinity Capture-MS Homo sapiens
54 SEMA4C 54910
Affinity Capture-MS Homo sapiens
55 PEX3 8504
Affinity Capture-MS Homo sapiens
56 MMP14 4323
Affinity Capture-MS Homo sapiens
57 EPHA1 2041
Affinity Capture-MS Homo sapiens
58 SFXN2  
Affinity Capture-MS Homo sapiens
59 NFXL1 152518
Affinity Capture-MS Homo sapiens
60 TNFSF9  
Affinity Capture-MS Homo sapiens
61 ITM2B 9445
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which LRRN4CL is involved
No pathways found





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