Gene ontology annotations for PODXL2
Experiment description of studies that identified PODXL2 in exosomes
1
Experiment ID
1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34887515
Organism
Homo sapiens
Experiment description
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors
"Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Colorectal cancer cells
Sample name
DiFi
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein miRNA
Methods used in the study
Western blotting Mass spectrometry RNA sequencing
2
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
3
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for PODXL2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
VCAM1
7412
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
2
UFSP2
55325
Affinity Capture-MS
Homo sapiens
3
SLC39A12
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
4
CRLF2
64109
Affinity Capture-MS
Homo sapiens
5
LMAN2
10960
Affinity Capture-MS
Homo sapiens
6
RAET1E
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
MECP2
4204
Affinity Capture-MS
Homo sapiens
8
PCDHGB1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
PRPH2
5961
Affinity Capture-MS
Homo sapiens
10
GALNT2
2590
Affinity Capture-MS
Homo sapiens
11
FCGRT
2217
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
12
TNFSF8
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
13
CD1B
910
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
14
TMEM30B
161291
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
15
SLC9A3R2
9351
Affinity Capture-MS
Homo sapiens
16
LAMP2
3920
Proximity Label-MS
Homo sapiens
17
TMX1
81542
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
18
ARF6
382
Proximity Label-MS
Homo sapiens
19
CEACAM21
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
20
LRRN4CL
221091
Affinity Capture-MS
Homo sapiens
21
TNFSF18
8995
Affinity Capture-MS
Homo sapiens
22
SMIM5
Affinity Capture-MS
Homo sapiens
23
PDCD1LG2
80380
Affinity Capture-MS
Homo sapiens
24
KIAA1429
25962
Affinity Capture-MS
Homo sapiens
25
PODXL2
50512
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
26
MOV10
4343
Affinity Capture-RNA
Homo sapiens
27
CTLA4
Affinity Capture-MS
Homo sapiens
28
RAB11A
8766
Proximity Label-MS
Homo sapiens
29
SLC9A3R1
9368
Affinity Capture-MS
Homo sapiens
30
RHPN1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
31
TGFA
Affinity Capture-MS
Homo sapiens
32
KRAS
3845
Proximity Label-MS
Homo sapiens
33
SLC47A1
Affinity Capture-MS
Homo sapiens
34
TPBG
7162
Affinity Capture-MS
Homo sapiens
35
RYK
6259
Affinity Capture-MS
Homo sapiens
36
CD63
967
Affinity Capture-MS
Homo sapiens
37
SELL
6402
Reconstituted Complex
Homo sapiens
38
B3GALT5
Affinity Capture-MS
Homo sapiens
39
ITFG3
83986
Affinity Capture-MS
Homo sapiens
40
CLRN2
Affinity Capture-MS
Homo sapiens
View the network
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Pathways in which PODXL2 is involved