Gene description for SPRYD3
Gene name SPRY domain containing 3
Gene symbol SPRYD3
Other names/aliases -
Species Homo sapiens
 Database cross references - SPRYD3
ExoCarta ExoCarta_84926
Vesiclepedia VP_84926
Entrez Gene 84926
HGNC 25920
UniProt Q8NCJ5  
 SPRYD3 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for SPRYD3
 Experiment description of studies that identified SPRYD3 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SPRYD3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 CETN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FBXO45 200933
Affinity Capture-MS Homo sapiens
4 INHBE 83729
Affinity Capture-MS Homo sapiens
5 Skp1a 21402
Affinity Capture-MS Mus musculus
6 SKP1 6500
Affinity Capture-MS Homo sapiens
7 MAP4 4134
Affinity Capture-MS Homo sapiens
8 YWHAZ 7534
Affinity Capture-MS Homo sapiens
9 USP11 8237
Affinity Capture-MS Homo sapiens
10 IGFBP4 3487
Affinity Capture-MS Homo sapiens
11 LRRN4CL 221091
Affinity Capture-MS Homo sapiens
12 MMP13  
Affinity Capture-MS Homo sapiens
13 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 CLEC11A 6320
Affinity Capture-MS Homo sapiens
15 Flnb 286940
Affinity Capture-MS Mus musculus
16 VCP 7415
Affinity Capture-MS Homo sapiens
17 TRIM21 6737
Affinity Capture-MS Homo sapiens
18 HEY1  
Affinity Capture-MS Homo sapiens
19 FBXW7  
Affinity Capture-MS Homo sapiens
20 ALPK2  
Affinity Capture-MS Homo sapiens
21 TDGF1  
Affinity Capture-MS Homo sapiens
22 HECTD1 25831
Affinity Capture-MS Homo sapiens
23 YWHAG 7532
Affinity Capture-MS Homo sapiens
24 Lgals3bp 19039
Affinity Capture-MS Mus musculus
25 IGFL3  
Affinity Capture-MS Homo sapiens
26 NMNAT2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SPRYD3 is involved
No pathways found





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