|
 Gene description for CSN1S1 |
| Gene name |
casein alpha s1 |
| Gene symbol |
CSN1S1 |
| Other names/aliases |
CASA
CSN1 |
| Species |
Homo sapiens |
| Database cross references - CSN1S1 |
| ExoCarta |
ExoCarta_1446 |
| Entrez Gene |
1446 |
| HGNC |
2445 |
| MIM |
115450 |
| UniProt |
P47710
|
| CSN1S1 identified in exosomes derived from the following tissue/cell type |
|
Breast milk
|
17641064
|
|
Breast milk
|
17641064
|
| Gene ontology annotations for CSN1S1 |
|
|
| Experiment description of studies that identified CSN1S1 in exosomes |
| 1 |
| Experiment ID |
46 |
| ISEV standards |
|
✔
EM|IEM
|
EV Biophysical techniques |
|
✔
HSC70
|
EV Cytosolic markers |
|
✔
CD63|MHCII|CD81|CD86
|
EV Membrane markers |
|
✔
CANX
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
17641064
|
| Organism |
Homo sapiens |
| Experiment description |
Exosomes with immune modulatory features are present in human breast milk. |
| Authors |
Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
| Journal name |
JIMMU
|
| Publication year |
2007 |
| Sample |
Breast milk |
| Sample name |
Breast milk - Colostrum |
| Isolation/purification methods |
Differential centrifugation
Filtration
Sucrose density gradient |
| Flotation density |
1.10-1.18 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS |
|
|
| 2 |
| Experiment ID |
48 |
| ISEV standards |
|
✔
EM|IEM
|
EV Biophysical techniques |
|
✔
HSC70
|
EV Cytosolic markers |
|
✔
CD63|CD86|MHCII
|
EV Membrane markers |
|
✔
CANX
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
17641064
|
| Organism |
Homo sapiens |
| Experiment description |
Exosomes with immune modulatory features are present in human breast milk. |
| Authors |
Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
| Journal name |
JIMMU
|
| Publication year |
2007 |
| Sample |
Breast milk |
| Sample name |
Breast milk - Mature milk |
| Isolation/purification methods |
Differential centrifugation
Filtration
Sucrose density gradient |
| Flotation density |
1.10-1.18 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS |
|
|
| Protein-protein interactions for CSN1S1 |
|
|
| Pathways in which CSN1S1 is involved |
|
|
|
