Gene description for CD1A
Gene name CD1a molecule
Gene symbol CD1A
Other names/aliases CD1
FCB6
HTA1
R4
T6
Species Homo sapiens
 Database cross references - CD1A
ExoCarta ExoCarta_909
Vesiclepedia VP_909
Entrez Gene 909
HGNC 1634
MIM 188370
UniProt P06126  
 CD1A identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD1A
Molecular Function
    protein binding GO:0005515 IPI
    endogenous lipid antigen binding GO:0030883 IBA
    exogenous lipid antigen binding GO:0030884 IBA
    lipopeptide binding GO:0071723 IBA
Biological Process
    positive regulation of T cell mediated cytotoxicity GO:0001916 IBA
    adaptive immune response GO:0002250 IEA
    immune response GO:0006955 IBA
    immune response GO:0006955 NAS
    antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 IBA
    antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 IBA
Subcellular Localization
    extracellular space GO:0005615 IBA
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    endosome membrane GO:0010008 IEA
    membrane raft GO:0045121 IEA
 Experiment description of studies that identified CD1A in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SGCB 6443
Affinity Capture-MS Homo sapiens
2 TMEM9 252839
Affinity Capture-MS Homo sapiens
3 TTC13  
Affinity Capture-MS Homo sapiens
4 HFE  
Affinity Capture-MS Homo sapiens
5 SCNN1A  
Affinity Capture-MS Homo sapiens
6 FZD6 8323
Affinity Capture-MS Homo sapiens
7 ARV1  
Affinity Capture-MS Homo sapiens
8 GPX8 493869
Affinity Capture-MS Homo sapiens
9 SUSD1 64420
Affinity Capture-MS Homo sapiens
10 TMEM30A 55754
Affinity Capture-MS Homo sapiens
11 MFAP3  
Affinity Capture-MS Homo sapiens
12 CANX 821
Affinity Capture-MS Homo sapiens
13 DGAT1 8694
Two-hybrid Homo sapiens
14 RNF167 26001
Affinity Capture-MS Homo sapiens
15 BCKDHB 594
Affinity Capture-MS Homo sapiens
16 ENTPD6  
Affinity Capture-MS Homo sapiens
17 HLA-DQB1 3119
Affinity Capture-MS Homo sapiens
18 PRF1  
Affinity Capture-MS Homo sapiens
19 ERMP1 79956
Affinity Capture-MS Homo sapiens
20 TMEM120A 83862
Affinity Capture-MS Homo sapiens
21 EXTL3 2137
Affinity Capture-MS Homo sapiens
22 PON2 5445
Affinity Capture-MS Homo sapiens
23 CLPTM1 1209
Affinity Capture-MS Homo sapiens
24 POMGNT1 55624
Affinity Capture-MS Homo sapiens
25 ECEL1  
Affinity Capture-MS Homo sapiens
26 STIM1 6786
Affinity Capture-MS Homo sapiens
27 MR1  
Affinity Capture-MS Homo sapiens
28 SLC25A15  
Affinity Capture-MS Homo sapiens
29 TMEM67 91147
Affinity Capture-MS Homo sapiens
30 GATB  
Affinity Capture-MS Homo sapiens
31 VWA5A 4013
Co-fractionation Homo sapiens
32 SCARB1 949
Affinity Capture-MS Homo sapiens
33 TMEM59L  
Affinity Capture-MS Homo sapiens
34 ABHD12 26090
Affinity Capture-MS Homo sapiens
35 GALNT12 79695
Affinity Capture-MS Homo sapiens
36 GPR50  
Affinity Capture-MS Homo sapiens
37 SUN2 25777
Affinity Capture-MS Homo sapiens
38 TUBA4A 7277
Affinity Capture-MS Homo sapiens
39 GALNT13 114805
Affinity Capture-MS Homo sapiens
40 TUBB2B 347733
Affinity Capture-MS Homo sapiens
41 MOGS 7841
Affinity Capture-MS Homo sapiens
42 ITGA7 3679
Affinity Capture-MS Homo sapiens
43 PBXIP1 57326
Affinity Capture-MS Homo sapiens
44 EXT2 2132
Affinity Capture-MS Homo sapiens
45 MAN1A2 10905
Affinity Capture-MS Homo sapiens
46 HLA-DPA1  
Affinity Capture-MS Homo sapiens
47 KCNJ8  
Affinity Capture-MS Homo sapiens
48 RAD21 5885
Affinity Capture-MS Homo sapiens
49 SEL1L3  
Affinity Capture-MS Homo sapiens
50 CLSTN3 9746
Affinity Capture-MS Homo sapiens
51 HLA-F 3134
Affinity Capture-MS Homo sapiens
52 HLA-B 3106
Affinity Capture-MS Homo sapiens
53 INTS7  
Affinity Capture-MS Homo sapiens
54 STIM2 57620
Affinity Capture-MS Homo sapiens
55 WNT5A 7474
Affinity Capture-MS Homo sapiens
56 RAB3B 5865
Affinity Capture-MS Homo sapiens
57 UBTD1 80019
Two-hybrid Homo sapiens
58 DSC2 1824
Affinity Capture-MS Homo sapiens
59 CERS6  
Affinity Capture-MS Homo sapiens
60 ENTPD2 954
Affinity Capture-MS Homo sapiens
61 LOC100507703  
Affinity Capture-MS Homo sapiens
62 ITGB5 3693
Affinity Capture-MS Homo sapiens
63 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
64 HLA-C 3107
Affinity Capture-MS Homo sapiens
65 KCTD5 54442
Two-hybrid Homo sapiens
66 SLC25A30 253512
Affinity Capture-MS Homo sapiens
67 MFGE8 4240
Affinity Capture-MS Homo sapiens
68 C1QL4  
Affinity Capture-MS Homo sapiens
69 CPT1A 1374
Affinity Capture-MS Homo sapiens
70 PURB 5814
Affinity Capture-MS Homo sapiens
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