Gene description for FBXL12
Gene name F-box and leucine-rich repeat protein 12
Gene symbol FBXL12
Other names/aliases Fbl12
Species Homo sapiens
 Database cross references - FBXL12
ExoCarta ExoCarta_54850
Entrez Gene 54850
HGNC 13611
MIM 609079
UniProt Q9NXK8  
 FBXL12 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for FBXL12
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    ubiquitin-dependent protein catabolic process GO:0006511 IEA
    protein ubiquitination GO:0016567 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    ubiquitin ligase complex GO:0000151 IEA
 Experiment description of studies that identified FBXL12 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FBXL12
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FXYD3 5349
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which FBXL12 is involved
No pathways found





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