Gene description for RNF111
Gene name	ring finger protein 111
Gene symbol	RNF111
Other names/aliases	ARK
Species	Homo sapiens
Database cross references - RNF111
ExoCarta	ExoCarta_54778
Entrez Gene	54778
HGNC	17384
MIM	605840
UniProt	Q6ZNA4
RNF111 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for RNF111

Molecular Function     protein binding GO:0005515 IPI     ligase activity GO:0016874 IEA     ubiquitin protein ligase activity GO:0061630 IMP     SUMO polymer binding GO:0032184 IDA     zinc ion binding GO:0008270 IEA     SMAD binding GO:0046332 IEA Biological Process     protein ubiquitination GO:0016567 IMP     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     ubiquitin-dependent SMAD protein catabolic process GO:0030579 IEA     positive regulation of protein ubiquitination GO:0031398 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 TAS     gene expression GO:0010467 TAS     transcription, DNA-templated GO:0006351 TAS     positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 IEA     positive regulation of transcription, DNA-templated GO:0045893 IMP     transforming growth factor beta receptor signaling pathway GO:0007179 TAS     pattern specification process GO:0007389 IEA     protein polyubiquitination GO:0000209 IEA Subcellular Localization     nucleolus GO:0005730 IDA     protein complex GO:0043234 IEA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     nucleus GO:0005634 IDA