Gene description for CGGBP1
Gene name CGG triplet repeat binding protein 1
Gene symbol CGGBP1
Other names/aliases CGGBP
p20-CGGBP
Species Homo sapiens
 Database cross references - CGGBP1
ExoCarta ExoCarta_8545
Vesiclepedia VP_8545
Entrez Gene 8545
HGNC 1888
MIM 603363
UniProt Q9UFW8  
 CGGBP1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CGGBP1
Molecular Function
    double-stranded DNA binding GO:0003690 IDA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    DNA-binding transcription factor binding GO:0140297 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    regulation of gene expression GO:0010468 IBA
    epigenetic regulation of gene expression GO:0040029 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified CGGBP1 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CGGBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CGGBP1 8545
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 MECP2 4204
Affinity Capture-MS Homo sapiens
3 MRM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
4 FBXL6  
Affinity Capture-MS Homo sapiens
5 FASN 2194
Positive Genetic Homo sapiens
6 SDCBP 6386
Two-hybrid Homo sapiens
7 RBPJ 3516
Affinity Capture-MS Homo sapiens
8 POLR1C 9533
Two-hybrid Homo sapiens
9 KLHL8  
Affinity Capture-MS Homo sapiens
10 SPIN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 REL 5966
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
12 BOLA2B 654483
Two-hybrid Homo sapiens
13 CDC37 11140
Two-hybrid Homo sapiens
14 ZZEF1 23140
Affinity Capture-MS Homo sapiens
15 FOXA1  
Affinity Capture-MS Homo sapiens
16 PLEKHF2 79666
Two-hybrid Homo sapiens
17 UBE3A 7337
Two-hybrid Homo sapiens
18 RBX1 9978
Affinity Capture-MS Homo sapiens
19 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
20 MKI67  
Affinity Capture-MS Homo sapiens
21 WDTC1 23038
Affinity Capture-MS Homo sapiens
22 APEX1 328
Co-fractionation Homo sapiens
23 MYCN  
Affinity Capture-MS Homo sapiens
24 MEMO1 51072
Affinity Capture-MS Homo sapiens
25 MYC  
Affinity Capture-MS Homo sapiens
26 FAM124A  
Two-hybrid Homo sapiens
27 WDYHV1  
Two-hybrid Homo sapiens
28 DDB1 1642
Co-fractionation Homo sapiens
29 GORASP2 26003
Two-hybrid Homo sapiens
30 RNF111 54778
Affinity Capture-MS Homo sapiens
31 FBXW7  
Affinity Capture-MS Homo sapiens
32 KCTD17 79734
Affinity Capture-MS Homo sapiens
33 GLRX3 10539
Two-hybrid Homo sapiens
34 FKBP3 2287
Co-fractionation Homo sapiens
35 NPM1 4869
Affinity Capture-MS Homo sapiens
36 SNRNP27  
Affinity Capture-MS Homo sapiens
37 CDKN2D  
Two-hybrid Homo sapiens
38 AKT1 207
Biochemical Activity Homo sapiens
39 Eif3e 16341
Affinity Capture-MS Mus musculus
40 BOLA2 552900
Two-hybrid Homo sapiens
41 CEBPA  
Protein-peptide Homo sapiens
42 SPIN2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CGGBP1 is involved
No pathways found





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