Gene description for CGGBP1
Gene name CGG triplet repeat binding protein 1
Gene symbol CGGBP1
Other names/aliases CGGBP
p20-CGGBP
Species Homo sapiens
 Database cross references - CGGBP1
ExoCarta ExoCarta_8545
Entrez Gene 8545
HGNC 1888
MIM 603363
UniProt Q9UFW8  
 CGGBP1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CGGBP1
Molecular Function
    RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 IMP
    protein binding GO:0005515 IPI
    double-stranded DNA binding GO:0003690 TAS
    RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription GO:0001227 IMP
Biological Process
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified CGGBP1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CGGBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CGGBP1 is involved
No pathways found





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