Experiment description of studies that identified TSPYL1 in exosomes

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for TSPYL1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 PSMA6 5687 Two-hybrid Homo sapiens 2 SENP3 26168 Affinity Capture-MS Homo sapiens 3 ZMYND8 23613 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 COIL   Proximity Label-MS Homo sapiens 5 AKAP11 11215 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 MDFI   Two-hybrid Homo sapiens 7 RPL15 6138 Affinity Capture-MS Homo sapiens 8 TYROBP   Affinity Capture-MS Homo sapiens 9 BRD2   Affinity Capture-MS Homo sapiens 10 CSNK2A1 1457 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 PRPF3   Two-hybrid Homo sapiens 12 DVL3 1857 Two-hybrid Homo sapiens 13 SNX6 58533 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 APP 351 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 15 C9orf78 51759 Affinity Capture-MS Homo sapiens 16 RPL10A 4736 Affinity Capture-MS Homo sapiens 17 RBM28 55131 Affinity Capture-MS Homo sapiens 18 TFAM 7019 Affinity Capture-MS Homo sapiens 19 EVI5L   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 DDX24 57062 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 21 NPM1 4869 Affinity Capture-MS Homo sapiens 22 PUSL1   Affinity Capture-MS Homo sapiens 23 DDX58 23586 Affinity Capture-RNA Homo sapiens 24 AMER1   Affinity Capture-MS Homo sapiens 25 Set 56086 Affinity Capture-MS Mus musculus 26 PRKRA 8575 Affinity Capture-MS Homo sapiens 27 MRS2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 HAP1   Two-hybrid Homo sapiens 29 NPAS1   Affinity Capture-MS Homo sapiens 30 CSNK2B 1460 Affinity Capture-MS Homo sapiens 31 DVL2 1856 Affinity Capture-MS Homo sapiens 32 PSME3 10197 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 BSG 682 Affinity Capture-MS Homo sapiens 34 SPAG5 10615 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 KIFC1 3833 Affinity Capture-MS Homo sapiens 36 MRPS34 65993 Affinity Capture-MS Homo sapiens 37 CACNG7   Affinity Capture-MS Homo sapiens 38 RPL18A 6142 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 SIPA1L2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 SLX4   Affinity Capture-MS Homo sapiens 41 REXO4   Affinity Capture-MS Homo sapiens 42 HECTD1 25831 Affinity Capture-MS Homo sapiens 43 SPANXN2   Affinity Capture-MS Homo sapiens 44 LCA5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 PIPSL 266971 Affinity Capture-MS Homo sapiens 46 WDR46   Affinity Capture-MS Homo sapiens 47 STK3 6788 Affinity Capture-MS Homo sapiens 48 OGT 8473 Reconstituted Complex Homo sapiens 49 RPL10 6134 Affinity Capture-MS Homo sapiens 50 KIF20A 10112 Affinity Capture-MS Homo sapiens 51 RC3H2   Affinity Capture-MS Homo sapiens 52 TSPYL2   Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 NPTN 27020 Affinity Capture-MS Homo sapiens 54 CUL3 8452 Affinity Capture-MS Homo sapiens 55 RICTOR 253260 Affinity Capture-MS Homo sapiens 56 RPL3 6122 Affinity Capture-MS Homo sapiens 57 METTL21B   Affinity Capture-MS Homo sapiens 58 SDC2 6383 Affinity Capture-MS Homo sapiens 59 SYP   Affinity Capture-MS Homo sapiens 60 TRIM44   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 ZC3H18   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 SET 6418 Affinity Capture-MS Homo sapiens 63 MAGEA4 4103 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 64 ITPRIPL1   Affinity Capture-MS Homo sapiens 65 ZNF687   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 PCM1 5108 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 MRPS17 51373 Affinity Capture-MS Homo sapiens 68 ZC3H3   Affinity Capture-MS Homo sapiens 69 BRD3 8019 Affinity Capture-MS Homo sapiens 70 C9orf72   Affinity Capture-MS Homo sapiens 71 TSPYL4 23270 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 RPS16 6217 Affinity Capture-MS Homo sapiens 73 FTL 2512 Affinity Capture-MS Homo sapiens 74 RPL13 6137 Affinity Capture-MS Homo sapiens 75 KIAA0232 9778 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 SURF6   Affinity Capture-MS Homo sapiens 77 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 78 RPL6 6128 Affinity Capture-MS Homo sapiens 79 IGHD   Affinity Capture-MS Homo sapiens 80 NAP1L3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 81 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 82 NAP1L2   Affinity Capture-MS Homo sapiens 83 TSPYL1 7259 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 84 FAM83H 286077 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 85 SIRT1   Affinity Capture-MS Homo sapiens 86 ESR1   Affinity Capture-MS Homo sapiens 87 OSBPL3 26031 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 88 ZBTB9   Two-hybrid Homo sapiens 89 ZCCHC10   Affinity Capture-MS Homo sapiens 90 GPC3 2719 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 91 RNF111 54778 Two-hybrid Homo sapiens 92 RPL8 6132 Affinity Capture-MS Homo sapiens 93 CCDC136   Two-hybrid Homo sapiens 94 LURAP1   Affinity Capture-MS Homo sapiens View the network

Pathways in which TSPYL1 is involved

No pathways found