Gene description for TSPYL1
Gene name TSPY-like 1
Gene symbol TSPYL1
Other names/aliases TSPYL
Species Homo sapiens
 Database cross references - TSPYL1
ExoCarta ExoCarta_7259
Entrez Gene 7259
HGNC 12382
MIM 604714
UniProt Q9H0U9  
 TSPYL1 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for TSPYL1
Molecular Function
    enzyme binding GO:0019899 IPI
Biological Process
    nucleosome assembly GO:0006334 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    nucleolus GO:0005730 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified TSPYL1 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for TSPYL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HAP1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which TSPYL1 is involved
No pathways found





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