Gene description for KIFC1
Gene name kinesin family member C1
Gene symbol KIFC1
Other names/aliases HSET
KNSL2
Species Homo sapiens
 Database cross references - KIFC1
ExoCarta ExoCarta_3833
Vesiclepedia VP_3833
Entrez Gene 3833
HGNC 6389
MIM 603763
UniProt Q9BW19  
 KIFC1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for KIFC1
Molecular Function
    microtubule motor activity GO:0003777 IBA
    microtubule motor activity GO:0003777 NAS
    ATP binding GO:0005524 NAS
    microtubule binding GO:0008017 IBA
    ATP hydrolysis activity GO:0016887 IBA
Biological Process
    mitotic sister chromatid segregation GO:0000070 NAS
    microtubule-based movement GO:0007018 IBA
    mitotic metaphase chromosome alignment GO:0007080 IMP
    cell division GO:0051301 IEA
    mitotic spindle assembly GO:0090307 IBA
    mitotic spindle assembly GO:0090307 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    early endosome GO:0005769 IEA
    centrosome GO:0005813 IEA
    microtubule organizing center GO:0005815 IBA
    kinesin complex GO:0005871 IBA
    microtubule GO:0005874 IBA
    membrane GO:0016020 HDA
    mitotic spindle GO:0072686 IBA
 Experiment description of studies that identified KIFC1 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KIFC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNL2 29889
Affinity Capture-MS Homo sapiens
2 CD3EAP  
Proximity Label-MS Homo sapiens
3 WDR46  
Affinity Capture-MS Homo sapiens
4 MPG 4350
Co-fractionation Homo sapiens
5 PHLPP1  
Proximity Label-MS Homo sapiens
6 ATG16L1 55054
Affinity Capture-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 MYCN  
Affinity Capture-MS Homo sapiens
9 PARP1 142
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
10 HIST1H3A 8350
Proximity Label-MS Homo sapiens
11 COIL  
Proximity Label-MS Homo sapiens
12 FEV  
Proximity Label-MS Homo sapiens
13 ARPC2 10109
Affinity Capture-MS Homo sapiens
14 TNPO1 3842
Affinity Capture-MS Homo sapiens
15 RALBP1 10928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 UBXN7 26043
Affinity Capture-MS Homo sapiens
17 RPL35 11224
Affinity Capture-MS Homo sapiens
18 CXXC1  
Affinity Capture-Western Homo sapiens
19 KPNB1 3837
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 KLF8  
Proximity Label-MS Homo sapiens
21 RPS6 6194
Proximity Label-MS Homo sapiens
22 RPA3 6119
Proximity Label-MS Homo sapiens
23 KPNA2 3838
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 PARK2  
Affinity Capture-MS Homo sapiens
25 RBM28 55131
Affinity Capture-MS Homo sapiens
26 METTL21B  
Affinity Capture-MS Homo sapiens
27 XRCC6 2547
Proximity Label-MS Homo sapiens
28 RGPD1  
Affinity Capture-MS Homo sapiens
29 APP 351
Reconstituted Complex Homo sapiens
30 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
31 REXO4  
Affinity Capture-MS Homo sapiens
32 CENPA  
Proximity Label-MS Homo sapiens
33 SOX15  
Proximity Label-MS Homo sapiens
34 CBX3 11335
Proximity Label-MS Homo sapiens
35 KRR1 11103
Affinity Capture-MS Homo sapiens
36 NUP50 10762
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 MRPS10 55173
Affinity Capture-MS Homo sapiens
38 TFAM 7019
Affinity Capture-MS Homo sapiens
39 TSPYL1 7259
Affinity Capture-MS Homo sapiens
40 BAG1 573
Co-fractionation Homo sapiens
41 STK10 6793
Co-fractionation Homo sapiens
42 RAN 5901
Affinity Capture-MS Homo sapiens
43 CEBPZ  
Affinity Capture-MS Homo sapiens
44 NKRF 55922
Two-hybrid Homo sapiens
45 SET 6418
Affinity Capture-MS Homo sapiens
46 Nek2  
Affinity Capture-MS Mus musculus
47 REPIN1  
Affinity Capture-MS Homo sapiens
48 U2AF2 11338
Affinity Capture-MS Homo sapiens
49 NUP153 9972
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 RRP12 23223
Affinity Capture-MS Homo sapiens
51 EP300 2033
Affinity Capture-MS Homo sapiens
52 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
53 PPAN 56342
Affinity Capture-MS Homo sapiens
54 DDRGK1 65992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 AR 367
Proximity Label-MS Homo sapiens
56 HECTD1 25831
Affinity Capture-MS Homo sapiens
57 FAM188A 80013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 TEAD1  
Proximity Label-MS Homo sapiens
59 CCT8L2  
Affinity Capture-MS Homo sapiens
60 Pdlim5 56376
Affinity Capture-MS Mus musculus
61 EPS15L1 58513
Affinity Capture-MS Homo sapiens
62 CEBPA  
Protein-peptide Homo sapiens
63 CCDC8  
Affinity Capture-MS Homo sapiens
64 NUSAP1 51203
Affinity Capture-MS Homo sapiens
65 PARD6B 84612
Affinity Capture-MS Homo sapiens
66 DYNC2LI1 51626
Affinity Capture-MS Homo sapiens
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