Gene description for KIFC1
Gene name kinesin family member C1
Gene symbol KIFC1
Other names/aliases HSET
KNSL2
Species Homo sapiens
 Database cross references - KIFC1
ExoCarta ExoCarta_3833
Entrez Gene 3833
HGNC 6389
MIM 603763
UniProt Q9BW19  
 KIFC1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for KIFC1
Molecular Function
    ATP binding GO:0005524 NAS
    microtubule motor activity GO:0003777 NAS
    microtubule binding GO:0008017 IEA
    ATP-dependent microtubule motor activity, minus-end-directed GO:0008569 IBA
Biological Process
    blood coagulation GO:0007596 TAS
    mitotic spindle assembly GO:0090307 IMP
    microtubule-based movement GO:0007018 TAS
    metabolic process GO:0008152 NAS
    mitotic metaphase plate congression GO:0007080 IMP
    mitotic sister chromatid segregation GO:0000070 NAS
    cell division GO:0051301 IEA
Subcellular Localization
    spindle GO:0005819 IEA
    microtubule GO:0005874 IEA
    nucleus GO:0005634 IEA
    kinesin complex GO:0005871 IBA
    membrane GO:0016020 IDA
    microtubule organizing center GO:0005815 IEA
    early endosome GO:0005769 IEA
 Experiment description of studies that identified KIFC1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KIFC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KIFC1 is involved
PathwayEvidenceSource
Kinesins TAS Reactome





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