Gene description for SKI
Gene name	SKI proto-oncogene
Gene symbol	SKI
Other names/aliases	SGS SKV
Species	Homo sapiens
Database cross references - SKI
ExoCarta	ExoCarta_6497
Entrez Gene	6497
HGNC	10896
MIM	164780
UniProt	P12755
SKI identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for SKI

Molecular Function     transcription corepressor activity GO:0003714 IMP     protein domain specific binding GO:0019904 IPI     chromatin binding GO:0003682 IEA     protein kinase binding GO:0019901 IPI     zinc ion binding GO:0008270 IDA     protein binding GO:0005515 IPI     repressing transcription factor binding GO:0070491 IPI     histone deacetylase inhibitor activity GO:0046811 ISS     ubiquitin protein ligase binding GO:0031625 IPI     SMAD binding GO:0046332 IPI Biological Process     cell motility GO:0048870 NAS     camera-type eye development GO:0043010 ISS     cell proliferation GO:0008283 NAS     negative regulation of histone deacetylation GO:0031064 IEA     anterior/posterior axis specification GO:0009948 ISS     gene expression GO:0010467 TAS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 TAS     myotube differentiation GO:0014902 IDA     negative regulation of cell proliferation GO:0008285 IDA     BMP signaling pathway GO:0030509 TAS     bone morphogenesis GO:0060349 ISS     negative regulation of Schwann cell proliferation GO:0010626 IGI     regulation of apoptotic process GO:0042981 IBA     protein homotrimerization GO:0070207 IDA     embryonic limb morphogenesis GO:0030326 ISS     nose morphogenesis GO:0043585 ISS     myelination in peripheral nervous system GO:0022011 ISS     transforming growth factor beta receptor signaling pathway GO:0007179 TAS     negative regulation of BMP signaling pathway GO:0030514 IMP     negative regulation of activin receptor signaling pathway GO:0032926 IDA     olfactory bulb development GO:0021772 ISS     negative regulation of osteoblast differentiation GO:0045668 IDA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     somatic stem cell maintenance GO:0035019 ISS     palate development GO:0060021 ISS     lens morphogenesis in camera-type eye GO:0002089 ISS     skeletal muscle fiber development GO:0048741 ISS     face morphogenesis GO:0060325 ISS     positive regulation of DNA binding GO:0043388 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS     neural tube closure GO:0001843 ISS     transcription, DNA-templated GO:0006351 TAS     SMAD protein signal transduction GO:0060395 IDA     retina development in camera-type eye GO:0060041 ISS     camera-type eye morphogenesis GO:0048593 ISS     positive regulation of Wnt signaling pathway GO:0030177 NAS     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IMP     negative regulation of fibroblast proliferation GO:0048147 ISS Subcellular Localization     nuclear body GO:0016604 IDA     centrosome GO:0005813 IDA     transcription factor complex GO:0005667 ISS     PML body GO:0016605 IDA     transcriptional repressor complex GO:0017053 ISS     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 ISS     protein complex GO:0043234 IDA     nucleus GO:0005634 IDA