Gene description for TES
Gene name testin LIM domain protein
Gene symbol TES
Other names/aliases TESS
TESS-2
Species Homo sapiens
 Database cross references - TES
ExoCarta ExoCarta_26136
Entrez Gene 26136
HGNC 14620
MIM 606085
UniProt Q9UGI8  
 TES identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for TES
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    zinc ion binding GO:0008270 IDA
Biological Process
    negative regulation of cell proliferation GO:0008285 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    plasma membrane GO:0005886 IDA
    protein complex GO:0043234 IDA
    focal adhesion GO:0005925 IDA
    cytoplasm GO:0005737 IDA
    cell junction GO:0030054 IDA
 Experiment description of studies that identified TES in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TES
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZYX 7791
Reconstituted Complex Homo sapiens
2 RAB8B 51762
Affinity Capture-Western Homo sapiens
3 ENAH 55740
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
4 ACTN1 87
Affinity Capture-MS Homo sapiens
5 ACTA1 58
Affinity Capture-Western Homo sapiens
6 ACTL7A  
Affinity Capture-MS Homo sapiens
7 TRADD 8717
Invivo Homo sapiens
Two-hybrid Homo sapiens
8 TES 26136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 VASP 7408
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which TES is involved
No pathways found





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