Gene description for TCP11L1
Gene name t-complex 11, testis-specific-like 1
Gene symbol TCP11L1
Other names/aliases dJ85M6.3
Species Homo sapiens
 Database cross references - TCP11L1
ExoCarta ExoCarta_55346
Vesiclepedia VP_55346
Entrez Gene 55346
HGNC 25655
UniProt Q9NUJ3  
 TCP11L1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TCP11L1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    signal transduction GO:0007165 IBA
Subcellular Localization
    microtubule GO:0005874 IDA
 Experiment description of studies that identified TCP11L1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TCP11L1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 TUBB2A 7280
Affinity Capture-MS Homo sapiens
3 Tubb5 22154
Affinity Capture-MS Mus musculus
4 CNOT7 29883
Two-hybrid Homo sapiens
5 PPM1M  
Affinity Capture-MS Homo sapiens
6 HLA-DPB1 3115
Affinity Capture-MS Homo sapiens
7 TUBB 203068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 MAGEA12  
Two-hybrid Homo sapiens
9 ZNF836  
Affinity Capture-MS Homo sapiens
10 NEDD4 4734
Reconstituted Complex Homo sapiens
11 TTC5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 IPO4 79711
Two-hybrid Homo sapiens
13 SDCBP2 27111
Two-hybrid Homo sapiens
14 VPS52 6293
Two-hybrid Homo sapiens
15 TSHR 7253
Affinity Capture-MS Homo sapiens
16 LHX2  
Two-hybrid Homo sapiens
17 REL 5966
Two-hybrid Homo sapiens
18 C2orf27B  
Affinity Capture-MS Homo sapiens
19 IKBKG 8517
Reconstituted Complex Homo sapiens
20 RIPK3 11035
Affinity Capture-MS Homo sapiens
21 MGARP  
Affinity Capture-MS Homo sapiens
22 CUL3 8452
Affinity Capture-MS Homo sapiens
23 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 TUBB4B 10383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 PKD1L2  
Affinity Capture-MS Homo sapiens
26 PSMD4 5710
Two-hybrid Homo sapiens
27 F12  
Affinity Capture-MS Homo sapiens
28 LOC254896  
Affinity Capture-MS Homo sapiens
29 ERBB3 2065
Affinity Capture-MS Homo sapiens
30 DDIT4L  
Two-hybrid Homo sapiens
31 TUBB1 81027
Affinity Capture-MS Homo sapiens
32 TUBB4A 10382
Affinity Capture-MS Homo sapiens
33 TBCD 6904
Affinity Capture-MS Homo sapiens
34 TUBB6 84617
Affinity Capture-MS Homo sapiens
35 SPCS3 60559
Affinity Capture-MS Homo sapiens
36 FAM213B 127281
Two-hybrid Homo sapiens
37 Smc3 13006
Affinity Capture-MS Mus musculus
38 GZMH  
Affinity Capture-MS Homo sapiens
39 NAGS  
Affinity Capture-MS Homo sapiens
40 TUBA4A 7277
Affinity Capture-MS Homo sapiens
41 Hsph1 15505
Affinity Capture-MS Mus musculus
42 TUBB2B 347733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CDK20  
Affinity Capture-MS Homo sapiens
44 TUBA1B 10376
Affinity Capture-MS Homo sapiens
45 CDHR4  
Affinity Capture-MS Homo sapiens
46 IL12RB1  
Affinity Capture-MS Homo sapiens
47 NAAA  
Affinity Capture-MS Homo sapiens
48 TRIM21 6737
Two-hybrid Homo sapiens
49 OGT 8473
Reconstituted Complex Homo sapiens
50 MCM2 4171
Affinity Capture-MS Homo sapiens
51 CST11  
Affinity Capture-MS Homo sapiens
52 TSNAX 7257
Two-hybrid Homo sapiens
53 FAM174A 345757
Affinity Capture-MS Homo sapiens
54 BRD1 23774
Affinity Capture-MS Homo sapiens
55 TBX6  
Two-hybrid Homo sapiens
56 PLEKHS1  
Two-hybrid Homo sapiens
57 SNW1 22938
Two-hybrid Homo sapiens
58 ARPC5 10092
Affinity Capture-MS Homo sapiens
59 Mad2l1 56150
Affinity Capture-MS Mus musculus
60 HMG20A  
Two-hybrid Homo sapiens
61 VWA2 340706
Affinity Capture-MS Homo sapiens
62 Blzf1 66352
Affinity Capture-MS Mus musculus
63 ANKRD13A 88455
Affinity Capture-MS Homo sapiens
64 ERCC6L2  
Two-hybrid Homo sapiens
65 PRSS22 64063
Affinity Capture-MS Homo sapiens
66 SULT1C4  
Affinity Capture-MS Homo sapiens
67 KLHL14 57565
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TCP11L1 is involved
No pathways found





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