Gene description for VWA2
Gene name von Willebrand factor A domain containing 2
Gene symbol VWA2
Other names/aliases AMACO
CCSP-2
NET42
Species Homo sapiens
 Database cross references - VWA2
ExoCarta ExoCarta_340706
Entrez Gene 340706
HGNC 24709
UniProt Q5GFL6  
 VWA2 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for VWA2
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IDA
Biological Process
    regulation of insulin receptor signaling pathway GO:0046626 IMP
    protein homooligomerization GO:0051260 IDA
    calcium-independent cell-matrix adhesion GO:0007161 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    extracellular exosome GO:0070062 IDA
    basement membrane GO:0005604 IEA
 Experiment description of studies that identified VWA2 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for VWA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VWA2 is involved
No pathways found





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