Gene description for VWA2
Gene name
von Willebrand factor A domain containing 2
Gene symbol
VWA2
Other names/aliases
AMACO CCSP-2 NET42
Species
Homo sapiens
Database cross references - VWA2
ExoCarta
ExoCarta_340706
Vesiclepedia
VP_340706
Entrez Gene
340706
HGNC
24709
UniProt
Q5GFL6
VWA2 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells
34887515
Saliva
19199708
Gene ontology annotations for VWA2
Experiment description of studies that identified VWA2 in exosomes
1
Experiment ID
1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34887515
Organism
Homo sapiens
Experiment description
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors
"Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Colorectal cancer cells
Sample name
DiFi
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein miRNA
Methods used in the study
Western blotting Mass spectrometry RNA sequencing
2
Experiment ID
66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19199708
Organism
Homo sapiens
Experiment description
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors
"Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name
JPR
Publication year
2009
Sample
Saliva
Sample name
Saliva
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy
Protein-protein interactions for VWA2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
STUB1
10273
Affinity Capture-MS
Homo sapiens
2
HERC1
8925
Affinity Capture-MS
Homo sapiens
3
MTR
4548
Affinity Capture-MS
Homo sapiens
4
TCP11L1
55346
Affinity Capture-MS
Homo sapiens
5
CCZ1
51622
Affinity Capture-MS
Homo sapiens
6
TUBB
203068
Affinity Capture-MS
Homo sapiens
7
TRAF2
7186
Two-hybrid
Homo sapiens
8
HSPA8
3312
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
RIC8B
55188
Affinity Capture-MS
Homo sapiens
10
CPNE7
27132
Affinity Capture-MS
Homo sapiens
11
DDX19B
11269
Affinity Capture-MS
Homo sapiens
12
MISP
126353
Affinity Capture-MS
Homo sapiens
13
NUDCD3
23386
Affinity Capture-MS
Homo sapiens
14
MARCH7
Affinity Capture-MS
Homo sapiens
15
WDR73
Affinity Capture-MS
Homo sapiens
16
TUBA1A
7846
Affinity Capture-MS
Homo sapiens
17
UBB
7314
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
18
TCTEX1D2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
19
TANGO6
79613
Affinity Capture-MS
Homo sapiens
20
DDA1
Affinity Capture-MS
Homo sapiens
21
GNB2
2783
Affinity Capture-MS
Homo sapiens
22
CAD
790
Affinity Capture-MS
Homo sapiens
23
PPP2R5D
5528
Affinity Capture-MS
Homo sapiens
24
TUBB7P
56604
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
25
RECQL4
Affinity Capture-MS
Homo sapiens
26
KLF15
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
27
CBWD1
55871
Affinity Capture-MS
Homo sapiens
28
GET4
51608
Affinity Capture-MS
Homo sapiens
29
WDR47
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
30
TUBB8
347688
Affinity Capture-MS
Homo sapiens
31
HSPA2
3306
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which VWA2 is involved
No pathways found