Gene description for Blzf1
Gene name basic leucine zipper nuclear factor 1
Gene symbol Blzf1
Other names/aliases 1700030G05Rik
Blzf1l
Golgin-45
Jem-1
Species Mus musculus
 Database cross references - Blzf1
ExoCarta ExoCarta_66352
Entrez Gene 66352
UniProt Q8R2X8  
 Blzf1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Blzf1
Molecular Function
    enzyme binding GO:0019899 ISO
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 ISO
Biological Process
    vesicle-mediated transport GO:0016192 IEA
    Golgi organization GO:0007030 ISO
    Golgi to plasma membrane protein transport GO:0043001 ISO
    protein transport GO:0015031 IEA
    transport GO:0006810 IEA
Subcellular Localization
    Golgi membrane GO:0000139 ISO
    Golgi apparatus GO:0005794 IDA
    nucleus GO:0005634 ISA
    cytoplasm GO:0005737 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Blzf1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Blzf1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Blzf1 is involved
PathwayEvidenceSource
Golgi Cisternae Pericentriolar Stack Reorganization IEA Reactome





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