Gene description for TNKS
Gene name	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Gene symbol	TNKS
Other names/aliases	ARTD5 PARP-5a PARP5A PARPL TIN1 TINF1 TNKS1 pART5
Species	Homo sapiens
Database cross references - TNKS
ExoCarta	ExoCarta_8658
Entrez Gene	8658
HGNC	11941
MIM	603303
UniProt	O95271
TNKS identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894

Gene ontology annotations for TNKS

Molecular Function     NAD+ ADP-ribosyltransferase activity GO:0003950 TAS     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IDA Biological Process     protein polyubiquitination GO:0000209 IDA     mitotic spindle organization GO:0007052 TAS     mitotic nuclear division GO:0007067 IEA     positive regulation of telomere maintenance via telomerase GO:0032212 IMP     negative regulation of DNA binding GO:0043392 IDA     spindle assembly GO:0051225 TAS     Wnt signaling pathway GO:0016055 IEA     protein localization to chromosome, telomeric region GO:0070198 IMP     peptidyl-threonine phosphorylation GO:0018107 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     mRNA transport GO:0051028 IEA     peptidyl-serine phosphorylation GO:0018105 IDA     protein ADP-ribosylation GO:0006471 IDA     cell division GO:0051301 IEA     regulation of telomere maintenance via telomerase GO:0032210 IC     protein poly-ADP-ribosylation GO:0070212 IDA     protein auto-ADP-ribosylation GO:0070213 IDA     protein transport GO:0015031 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS Subcellular Localization     chromosome, telomeric region GO:0000781 IDA     nuclear membrane GO:0031965 TAS     nuclear pore GO:0005643 TAS     spindle pole GO:0000922 IEA     cytosol GO:0005829 TAS     pericentriolar material GO:0000242 TAS     chromosome, centromeric region GO:0000775 IEA     Golgi apparatus GO:0005794 IDA     nuclear chromosome, telomeric region GO:0000784 IDA     Golgi membrane GO:0000139 IEA