Gene description for ATAD3C
Gene name ATPase family, AAA domain containing 3C
Gene symbol ATAD3C
Other names/aliases -
Species Homo sapiens
 Database cross references - ATAD3C
ExoCarta ExoCarta_219293
Vesiclepedia VP_219293
Entrez Gene 219293
HGNC 32151
UniProt Q5T2N8  
 ATAD3C identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for ATAD3C
Molecular Function
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
Biological Process
    mitochondrion organization GO:0007005 IBA
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified ATAD3C in exosomes
1
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ATAD3C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLCD4  
Affinity Capture-MS Homo sapiens
2 DKK3 27122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
4 PTH1R  
Affinity Capture-MS Homo sapiens
5 MAGEA3  
Affinity Capture-MS Homo sapiens
6 METTL14  
Affinity Capture-MS Homo sapiens
7 KIF14 9928
Affinity Capture-MS Homo sapiens
8 ATAD3B 83858
Cross-Linking-MS (XL-MS) Homo sapiens
9 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
10 KIF20A 10112
Affinity Capture-MS Homo sapiens
11 PLEKHM3 389072
Affinity Capture-MS Homo sapiens
12 PHKG2 5261
Affinity Capture-MS Homo sapiens
13 ATAD3A 55210
Cross-Linking-MS (XL-MS) Homo sapiens
14 AURKB 9212
Affinity Capture-MS Homo sapiens
15 GDE1 51573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 PARD6B 84612
Affinity Capture-MS Homo sapiens
17 KIF23 9493
Affinity Capture-MS Homo sapiens
18 MCM2 4171
Affinity Capture-MS Homo sapiens
19 DLST 1743
Affinity Capture-MS Homo sapiens
20 RDH13  
Affinity Capture-MS Homo sapiens
21 BRD1 23774
Affinity Capture-MS Homo sapiens
22 SERBP1 26135
Affinity Capture-MS Homo sapiens
23 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
24 CUL7 9820
Affinity Capture-MS Homo sapiens
25 PRC1 9055
Affinity Capture-MS Homo sapiens
26 COMMD1 150684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ATAD3C is involved
No pathways found





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