Experiment description of studies that identified PLEKHM3 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for PLEKHM3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens 2 YWHAE 7531 Affinity Capture-MS Homo sapiens 3 YWHAQ 10971 Affinity Capture-MS Homo sapiens 4 MGAT5B   Affinity Capture-MS Homo sapiens 5 KIF1A 547 Affinity Capture-MS Homo sapiens 6 XPO4 64328 Affinity Capture-MS Homo sapiens 7 YWHAG 7532 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 CUL3 8452 Affinity Capture-MS Homo sapiens 9 YWHAZ 7534 Affinity Capture-MS Homo sapiens 10 RMND1 55005 Affinity Capture-MS Homo sapiens 11 LAMP2 3920 Proximity Label-MS Homo sapiens 12 ATAD3C 219293 Affinity Capture-MS Homo sapiens 13 ENDOD1 23052 Affinity Capture-MS Homo sapiens 14 CANX 821 Affinity Capture-MS Homo sapiens 15 DEF8   Affinity Capture-MS Homo sapiens 16 LAMTOR1 55004 Proximity Label-MS Homo sapiens 17 RAB7A 7879 Proximity Label-MS Homo sapiens 18 LAMP3   Proximity Label-MS Homo sapiens 19 RAB9A 9367 Proximity Label-MS Homo sapiens 20 KIAA1549   Affinity Capture-MS Homo sapiens View the network

Pathways in which PLEKHM3 is involved

No pathways found