Gene description for MAP3K11
Gene name	mitogen-activated protein kinase kinase kinase 11
Gene symbol	MAP3K11
Other names/aliases	MEKK11 MLK-3 MLK3 PTK1 SPRK
Species	Homo sapiens
Database cross references - MAP3K11
ExoCarta	ExoCarta_4296
Vesiclepedia	VP_4296
Entrez Gene	4296
HGNC	6850
MIM	600050
UniProt	Q16584
MAP3K11 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for MAP3K11

Molecular Function     protein kinase activity GO:0004672 TAS     protein serine/threonine kinase activity GO:0004674 IDA     JUN kinase kinase kinase activity GO:0004706 IBA     JUN kinase kinase kinase activity GO:0004706 IMP     JUN kinase kinase kinase activity GO:0004706 ISS     MAP kinase kinase kinase activity GO:0004709 IMP     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     small GTPase binding GO:0031267 IEA     mitogen-activated protein kinase kinase binding GO:0031434 IEA     mitogen-activated protein kinase kinase kinase binding GO:0031435 IPI     identical protein binding GO:0042802 IPI     protein homodimerization activity GO:0042803 IPI     protein serine kinase activity GO:0106310 IEA Biological Process     MAPK cascade GO:0000165 IMP     protein phosphorylation GO:0006468 IDA     microtubule-based process GO:0007017 IBA     microtubule-based process GO:0007017 IMP     JNK cascade GO:0007254 IBA     JNK cascade GO:0007254 IMP     positive regulation of apoptotic process GO:0043065 IBA     positive regulation of JUN kinase activity GO:0043507 IMP     positive regulation of neuron apoptotic process GO:0043525 IEA     cell cycle G1/S phase transition GO:0044843 IMP     positive regulation of JNK cascade GO:0046330 IMP     protein autophosphorylation GO:0046777 IDA Subcellular Localization     cytoplasm GO:0005737 IBA     centrosome GO:0005813 IBA     centrosome GO:0005813 IDA     cytosol GO:0005829 TAS     microtubule GO:0005874 IDA     membrane GO:0016020 HDA