Gene description for KIF17
Gene name kinesin family member 17
Gene symbol KIF17
Other names/aliases KIF17B
Species Homo sapiens
 Database cross references - KIF17
ExoCarta ExoCarta_57576
Entrez Gene 57576
HGNC 19167
MIM 605037
UniProt Q9P2E2  
 KIF17 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIF17
Molecular Function
    microtubule binding GO:0008017 IEA
    ATP binding GO:0005524 IEA
    ATP-dependent microtubule motor activity, plus-end-directed GO:0008574 IBA
Biological Process
    protein transport GO:0015031 IEA
    microtubule-based movement GO:0007018 IBA
    vesicle-mediated transport GO:0016192 IEA
    metabolic process GO:0008152 IEA
    protein complex localization GO:0031503 IEA
    organelle organization GO:0006996 TAS
    cell projection organization GO:0030030 IBA
Subcellular Localization
    axoneme GO:0005930 IEA
    photoreceptor connecting cilium GO:0032391 IEA
    primary cilium GO:0072372 TAS
    cytosol GO:0005829 TAS
    periciliary membrane compartment GO:1990075 IEA
    microtubule GO:0005874 IEA
    intraciliary transport particle B GO:0030992 IEA
    ciliary basal body GO:0036064 IEA
    kinesin complex GO:0005871 IBA
 Experiment description of studies that identified KIF17 in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIF17
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAP3K11 4296
Two-hybrid Homo sapiens
2 XPO1 7514
Invivo Homo sapiens
Two-hybrid Homo sapiens
3 FHL5 9457
Invitro Homo sapiens
Invivo Homo sapiens
Two-hybrid Homo sapiens
4 MAP3K10  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KIF17 is involved
Intraflagellar transport TAS Reactome

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