Gene description for C6orf62
Gene name chromosome 6 open reading frame 62
Gene symbol C6orf62
Other names/aliases Nbla00237
XTP12
dJ30M3.2
Species Homo sapiens
 Database cross references - C6orf62
ExoCarta ExoCarta_81688
Vesiclepedia VP_81688
Entrez Gene 81688
HGNC 20998
UniProt Q9GZU0  
 C6orf62 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for C6orf62
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
 Experiment description of studies that identified C6orf62 in exosomes
1
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for C6orf62
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAP2K7 5609
Affinity Capture-MS Homo sapiens
2 TPP2 7174
Affinity Capture-MS Homo sapiens
3 VPS36 51028
Affinity Capture-MS Homo sapiens
4 PVRL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 XRCC1 7515
Affinity Capture-MS Homo sapiens
6 ASB6 140459
Affinity Capture-MS Homo sapiens
7 LIG3 3980
Affinity Capture-MS Homo sapiens
8 COX5B 1329
Affinity Capture-MS Homo sapiens
9 SLC22A4 6583
Affinity Capture-MS Homo sapiens
10 FDX1L  
Affinity Capture-MS Homo sapiens
11 UBE4A 9354
Affinity Capture-MS Homo sapiens
12 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
13 VPS25 84313
Affinity Capture-MS Homo sapiens
14 KIF14 9928
Affinity Capture-MS Homo sapiens
15 HAL 3034
Affinity Capture-MS Homo sapiens
16 PNKP 11284
Affinity Capture-MS Homo sapiens
17 ASUN  
Affinity Capture-MS Homo sapiens
18 SNF8 11267
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C6orf62 is involved
No pathways found





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