Gene description for SNX17
Gene name
sorting nexin 17
Gene symbol
SNX17
Other names/aliases
-
Species
Homo sapiens
Database cross references - SNX17
ExoCarta
ExoCarta_9784
Entrez Gene
9784
HGNC
14979
MIM
605963
UniProt
Q15036
SNX17 identified in exosomes derived from the following tissue/cell type
Hepatocytes
26054723
Thymus
23844026
Gene ontology annotations for SNX17
Experiment description of studies that identified SNX17 in exosomes
1
Experiment ID
237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SNX17
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
VLDLR
Invivo
Homo sapiens
Invitro
Homo sapiens
2
LDLR
3949
Invitro
Homo sapiens
Invivo
Homo sapiens
3
LRP8
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
4
SELP
6403
Two-hybrid
Homo sapiens
5
LRP1
4035
Invivo
Homo sapiens
Invitro
Homo sapiens
View the network
image/svg+xml
Pathways in which SNX17 is involved
No pathways found