Gene description for PGM3
Gene name phosphoglucomutase 3
Gene symbol PGM3
Other names/aliases AGM1
IMD23
PAGM
PGM 3
Species Homo sapiens
 Database cross references - PGM3
ExoCarta ExoCarta_5238
Entrez Gene 5238
HGNC 8907
MIM 172100
UniProt O95394  
 PGM3 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for PGM3
Molecular Function
    magnesium ion binding GO:0000287 IEA
    phosphoacetylglucosamine mutase activity GO:0004610 IMP
    phosphoglucomutase activity GO:0004614 IEA
Biological Process
    dolichol-linked oligosaccharide biosynthetic process GO:0006488 TAS
    spermatogenesis GO:0007283 IEA
    protein N-linked glycosylation via asparagine GO:0018279 TAS
    protein O-linked glycosylation GO:0006493 IMP
    post-translational protein modification GO:0043687 TAS
    glucosamine metabolic process GO:0006041 NAS
    glucose 1-phosphate metabolic process GO:0019255 IEA
    cellular protein metabolic process GO:0044267 TAS
    hemopoiesis GO:0030097 IBA
    UDP-N-acetylglucosamine biosynthetic process GO:0006048 TAS
    protein N-linked glycosylation GO:0006487 IMP
Subcellular Localization
    cytosol GO:0005829 TAS
    cellular_component GO:0005575 ND
 Experiment description of studies that identified PGM3 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PGM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PGM3 is involved
PathwayEvidenceSource
Synthesis of UDP-N-acetyl-glucosamine TAS Reactome





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