Gene description for PGM5
Gene name phosphoglucomutase 5
Gene symbol PGM5
Other names/aliases PGMRP
Species Homo sapiens
 Database cross references - PGM5
ExoCarta ExoCarta_5239
Entrez Gene 5239
HGNC 8908
MIM 600981
UniProt Q15124  
 PGM5 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for PGM5
Molecular Function
    magnesium ion binding GO:0000287 IEA
    phosphoglucomutase activity GO:0004614 IDA
    structural molecule activity GO:0005198 NAS
Biological Process
    glycogen biosynthetic process GO:0005978 IBA
    cell adhesion GO:0007155 IEA
    glucose metabolic process GO:0006006 IBA
    galactose catabolic process GO:0019388 IBA
Subcellular Localization
    cytosol GO:0005829 IBA
    focal adhesion GO:0005925 IDA
    cell-cell adherens junction GO:0005913 IDA
    sarcolemma GO:0042383 IDA
    spot adherens junction GO:0005914 IDA
    costamere GO:0043034 IDA
    intercalated disc GO:0014704 IDA
    stress fiber GO:0001725 IDA
    cytoplasmic side of plasma membrane GO:0009898 IDA
    dystrophin-associated glycoprotein complex GO:0016010 ISS
    Z disc GO:0030018 IBA
 Experiment description of studies that identified PGM5 in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PGM5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UTRN 7402
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which PGM5 is involved
No pathways found





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