Gene description for NOTCH3
Gene name	notch 3
Gene symbol	NOTCH3
Other names/aliases	CADASIL CASIL IMF2
Species	Homo sapiens
Database cross references - NOTCH3
ExoCarta	ExoCarta_4854
Entrez Gene	4854
HGNC	7883
MIM	600276
UniProt	Q9UM47
NOTCH3 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for NOTCH3

Molecular Function     enzyme binding GO:0019899 IEA     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI Biological Process     positive regulation of smooth muscle cell proliferation GO:0048661 IEA     negative regulation of neuron differentiation GO:0045665 IEA     Notch signaling pathway GO:0007219 TAS     gene expression GO:0010467 TAS     forebrain development GO:0030900 IEA     regulation of transcription, DNA-templated GO:0006355 IEA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     neuron fate commitment GO:0048663 IEA     Notch receptor processing GO:0007220 TAS     glomerular capillary formation GO:0072104 IEA Subcellular Localization     cytosol GO:0005829 TAS     integral component of membrane GO:0016021 IEA     extracellular region GO:0005576 TAS     endoplasmic reticulum membrane GO:0005789 TAS     Golgi membrane GO:0000139 TAS     actin cytoskeleton GO:0015629 IDA     nucleoplasm GO:0005654 TAS     plasma membrane GO:0005886 TAS     cytoplasm GO:0005737 IDA     receptor complex GO:0043235 IDA