Gene description for HNRNPCL3
Gene name heterogeneous nuclear ribonucleoprotein C-like 3
Gene symbol HNRNPCL3
Other names/aliases HNRNPCL2
Species Homo sapiens
 Database cross references - HNRNPCL3
ExoCarta ExoCarta_649330
Vesiclepedia VP_649330
Entrez Gene 649330
HGNC 51235
UniProt P0DMR1   B7ZW38  
 HNRNPCL3 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for HNRNPCL3
Molecular Function
    RNA binding GO:0003723 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified HNRNPCL3 in exosomes
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for HNRNPCL3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLXNA2 5362
Cross-Linking-MS (XL-MS) Homo sapiens
2 PPIP5K2 23262
Cross-Linking-MS (XL-MS) Homo sapiens
3 METTL18  
Affinity Capture-MS Homo sapiens
4 FASN 2194
Cross-Linking-MS (XL-MS) Homo sapiens
5 VDAC3 7419
Cross-Linking-MS (XL-MS) Homo sapiens
6 KIF20A 10112
Affinity Capture-MS Homo sapiens
7 PLXNA4 91584
Cross-Linking-MS (XL-MS) Homo sapiens
8 KIF14 9928
Affinity Capture-MS Homo sapiens
9 IFI16 3428
Affinity Capture-MS Homo sapiens
10 RPS19 6223
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which HNRNPCL3 is involved
No pathways found





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