Gene description for EXOSC4
Gene name	exosome component 4
Gene symbol	EXOSC4
Other names/aliases	RRP41 RRP41A Rrp41p SKI6 Ski6p hRrp41p p12A
Species	Homo sapiens
Database cross references - EXOSC4
ExoCarta	ExoCarta_54512
Entrez Gene	54512
HGNC	18189
MIM	606491
UniProt	Q9NPD3
EXOSC4 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for EXOSC4

Molecular Function     AU-rich element binding GO:0017091 IDA     protein binding GO:0005515 IPI     3'-5'-exoribonuclease activity GO:0000175 NAS     exoribonuclease activity GO:0004532 IDA Biological Process     rRNA catabolic process GO:0016075 IBA     DNA deamination GO:0045006 IDA     gene expression GO:0010467 TAS     nuclear mRNA surveillance GO:0071028 IMP     positive regulation of cell growth GO:0030307 IMP     histone mRNA catabolic process GO:0071044 IMP     rRNA 3'-end processing GO:0031125 IBA     nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' GO:0034427 IBA     exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 TAS     nuclear-transcribed mRNA catabolic process GO:0000956 IMP     maturation of 5.8S rRNA GO:0000460 IMP     U4 snRNA 3'-end processing GO:0034475 IBA     polyadenylation-dependent snoRNA 3'-end processing GO:0071051 IBA     RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 NAS     nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 TAS     rRNA processing GO:0006364 NAS     defense response to virus GO:0051607 IMP Subcellular Localization     cytoplasmic exosome (RNase complex) GO:0000177 IBA     nucleolus GO:0005730 NAS     nucleus GO:0005634 IDA     cytoplasm GO:0005737 NAS     exosome (RNase complex) GO:0000178 IDA     transcriptionally active chromatin GO:0035327 IMP     nuclear exosome (RNase complex) GO:0000176 IBA     cytosol GO:0005829 TAS