Experiment description of studies that identified PRPSAP1 in exosomes

1 Experiment ID 224 ISEV standards ✔ EM|AFM EV Biophysical techniques ✔ Alix|TSG101 EV Cytosolic markers ✔ CD63|CD81 EV Membrane markers ✔ GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

2 Experiment ID 217 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101 EV Cytosolic markers ✔ CD81|CD9|CD63 EV Membrane markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PRPSAP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CD2BP2 10421 Affinity Capture-MS Homo sapiens 2 PRPS2 5634 Invitro Homo sapiens Invivo Homo sapiens 3 CGI-119   Affinity Capture-MS Homo sapiens 4 ILK 3611 Affinity Capture-MS Homo sapiens 5 PTP4A3   Affinity Capture-MS Homo sapiens 6 PLEKHF2 79666 Two-hybrid Homo sapiens 7 ARK5   Affinity Capture-MS Homo sapiens 8 PRPS1 5631 Invitro Homo sapiens Invivo Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 9 PSPH 5723 Affinity Capture-MS Homo sapiens 10 PRKRA 8575 Affinity Capture-MS Homo sapiens 11 PRPSAP1 5635 Two-hybrid Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which PRPSAP1 is involved

No pathways found