Gene description for PIK3C3
Gene name	phosphatidylinositol 3-kinase, catalytic subunit type 3
Gene symbol	PIK3C3
Other names/aliases	VPS34 Vps34 hVps34
Species	Homo sapiens
Database cross references - PIK3C3
ExoCarta	ExoCarta_5289
Entrez Gene	5289
HGNC	8974
MIM	602609
UniProt	Q8NEB9
PIK3C3 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for PIK3C3

Molecular Function     protein kinase activity GO:0004672 IEA     1-phosphatidylinositol-3-kinase activity GO:0016303 IMP     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA Biological Process     insulin receptor signaling pathway GO:0008286 TAS     innate immune response GO:0045087 TAS     peroxisome degradation GO:0030242 IBA     macroautophagy GO:0016236 ISS     toll-like receptor signaling pathway GO:0002224 TAS     phospholipid metabolic process GO:0006644 TAS     phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 TAS     endosome organization GO:0007032 IEA     early endosome to late endosome transport GO:0045022 IMP     autophagosome assembly GO:0000045 IBA     cellular response to glucose starvation GO:0042149 ISS     toll-like receptor 9 signaling pathway GO:0034162 TAS     response to leucine GO:0043201 IEA     regulation of cytokinesis GO:0032465 IMP     phosphatidylinositol biosynthetic process GO:0006661 TAS     phosphatidylinositol-mediated signaling GO:0048015 IBA     endocytosis GO:0006897 IBA     cytokinesis GO:0000910 IMP     protein processing GO:0016485 IEA     small molecule metabolic process GO:0044281 TAS     phosphatidylinositol phosphorylation GO:0046854 IBA     protein phosphorylation GO:0006468 IBA     regulation of protein secretion GO:0050708 IEA Subcellular Localization     late endosome GO:0005770 IDA     phosphatidylinositol 3-kinase complex, class III, type I GO:0034271 IBA     phosphatidylinositol 3-kinase complex, class III GO:0035032 ISS     membrane GO:0016020 IDA     cytoplasm GO:0005737 IBA     peroxisome GO:0005777 IBA     axoneme GO:0005930 ISS     midbody GO:0030496 IDA     cytosol GO:0005829 TAS     phosphatidylinositol 3-kinase complex, class III, type II GO:0034272 IBA     phagocytic vesicle GO:0045335 IEA     pre-autophagosomal structure GO:0000407 IBA