Gene description for ZC2HC1A
Gene name zinc finger, C2HC-type containing 1A
Gene symbol ZC2HC1A
Other names/aliases C8orf70
CGI-62
FAM164A
Species Homo sapiens
 Database cross references - ZC2HC1A
ExoCarta ExoCarta_51101
Vesiclepedia VP_51101
Entrez Gene 51101
HGNC 24277
UniProt Q96GY0  
 ZC2HC1A identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ZC2HC1A
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
 Experiment description of studies that identified ZC2HC1A in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ZC2HC1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 MECP2 4204
Affinity Capture-MS Homo sapiens
3 MYCN  
Affinity Capture-MS Homo sapiens
4 WDR5 11091
Affinity Capture-MS Homo sapiens
5 Cep120  
Affinity Capture-MS Mus musculus
6 DGKG  
Affinity Capture-MS Homo sapiens
7 EXOC8 149371
Two-hybrid Homo sapiens
8 XPO1 7514
Affinity Capture-MS Homo sapiens
9 EGLN3  
Two-hybrid Homo sapiens
10 TUBB4B 10383
Affinity Capture-MS Homo sapiens
11 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
12 SOX2  
Affinity Capture-MS Homo sapiens
13 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
14 MAPRE1 22919
Proximity Label-MS Homo sapiens
15 GATSL3 652968
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
16 ERCC3  
Co-fractionation Homo sapiens
17 MAPRE3  
Proximity Label-MS Homo sapiens
18 PCBP1 5093
Affinity Capture-MS Homo sapiens
19 CDH1 999
Co-fractionation Homo sapiens
20 TUBA1B 10376
Affinity Capture-MS Homo sapiens
21 MYC  
Affinity Capture-MS Homo sapiens
22 BICD2 23299
Proximity Label-MS Homo sapiens
23 CAPS 828
Affinity Capture-MS Homo sapiens
24 TRIP4 9325
Affinity Capture-MS Homo sapiens
25 DCTN1 1639
Proximity Label-MS Homo sapiens
26 YES1 7525
Two-hybrid Homo sapiens
27 LASP1 3927
Two-hybrid Homo sapiens
28 COL8A1 1295
Affinity Capture-MS Homo sapiens
29 TUBA1C 84790
Affinity Capture-MS Homo sapiens
30 RAD54L2  
Two-hybrid Homo sapiens
31 SEC61B 10952
Affinity Capture-MS Homo sapiens
32 SP100 6672
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZC2HC1A is involved
No pathways found





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