Experiment description of studies that identified ADNP in exosomes

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for ADNP

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HIST2H2BE 8349 Affinity Capture-MS Homo sapiens 2 ZNF292   Affinity Capture-MS Homo sapiens 3 CBX1 10951 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 KPNA1 3836 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 MIS12   Affinity Capture-MS Homo sapiens 6 Gtf3c2   Affinity Capture-MS Mus musculus 7 RPS19BP1   Affinity Capture-MS Homo sapiens 8 POGZ 23126 Affinity Capture-MS Homo sapiens 9 NFATC1 4772 Affinity Capture-MS Homo sapiens 10 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 11 NSL1   Affinity Capture-MS Homo sapiens 12 ACTC1 70 Proximity Label-MS Homo sapiens 13 HIST1H2BJ 8970 Affinity Capture-MS Homo sapiens 14 SCAI   Affinity Capture-MS Homo sapiens 15 TRIM27   Affinity Capture-MS Homo sapiens 16 SEPT2 4735 Co-fractionation Homo sapiens 17 PMF1   Affinity Capture-MS Homo sapiens 18 CCDC71L   Affinity Capture-MS Homo sapiens 19 MAP1LC3B 81631 Two-hybrid Homo sapiens 20 CTNNB1 1499 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 21 CHAF1A   Affinity Capture-MS Homo sapiens 22 KLF8   Proximity Label-MS Homo sapiens 23 VARS 7407 Co-fractionation Homo sapiens 24 ZNF524   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 SYT2   Affinity Capture-MS Homo sapiens 26 HADHA 3030 Co-fractionation Homo sapiens 27 THRSP   Affinity Capture-MS Homo sapiens 28 ARID1A 8289 Affinity Capture-MS Homo sapiens 29 DYNLL1 8655 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 KPNA4 3840 Co-fractionation Homo sapiens 31 ILK 3611 Affinity Capture-MS Homo sapiens 32 ZNF644   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 PHF7   Affinity Capture-MS Homo sapiens 34 ZSCAN20   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 MECP2 4204 Affinity Capture-MS Homo sapiens 36 MYCN   Affinity Capture-MS Homo sapiens 37 WDR5 11091 Affinity Capture-MS Homo sapiens 38 CSNK2B 1460 Affinity Capture-MS Homo sapiens 39 MAD2L1 4085 Affinity Capture-MS Homo sapiens 40 USP37   Proximity Label-MS Homo sapiens 41 KIF14 9928 Affinity Capture-MS Homo sapiens 42 LIN28A   Affinity Capture-MS Homo sapiens 43 H2AFZ 3015 Affinity Capture-MS Homo sapiens 44 ZKSCAN8   Affinity Capture-MS Homo sapiens 45 FOXC1   Affinity Capture-MS Homo sapiens 46 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 47 FHL3 2275 Affinity Capture-MS Homo sapiens 48 EMD 2010 Co-fractionation Homo sapiens 49 QPRT 23475 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 WHSC1 7468 Proximity Label-MS Homo sapiens 51 MAP1B 4131 Co-fractionation Homo sapiens 52 MGA   Affinity Capture-MS Homo sapiens 53 LRIF1   Affinity Capture-MS Homo sapiens 54 CBX3 11335 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 SMARCA4 6597 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 56 HDAC7   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 NFIA 4774 Co-fractionation Homo sapiens 58 NTRK1 4914 Affinity Capture-MS Homo sapiens 59 AIM2   Affinity Capture-MS Homo sapiens 60 CBX5 23468 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 TEAD2   Affinity Capture-MS Homo sapiens 62 RPA4   Proximity Label-MS Homo sapiens 63 PHGDH 26227 Co-fractionation Homo sapiens 64 ZNF581   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 NOL4   Affinity Capture-MS Homo sapiens 66 DYNLL2 140735 Affinity Capture-MS Homo sapiens 67 EED   Affinity Capture-MS Homo sapiens 68 KPNA5 3841 Affinity Capture-MS Homo sapiens 69 CEBPA   Proximity Label-MS Homo sapiens 70 FOXS1   Affinity Capture-MS Homo sapiens 71 DAXX   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 SMARCC2 6601 Affinity Capture-MS Homo sapiens 73 DSN1 79980 Affinity Capture-MS Homo sapiens 74 POLG2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 NUMA1 4926 Affinity Capture-MS Homo sapiens 76 SLX4   Affinity Capture-MS Homo sapiens 77 FOXK2   Affinity Capture-MS Homo sapiens 78 HIST1H3A 8350 Proximity Label-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 79 FANCD2   Affinity Capture-MS Homo sapiens 80 CUL3 8452 Affinity Capture-MS Homo sapiens 81 AHDC1   Affinity Capture-MS Homo sapiens 82 PIP 5304 Affinity Capture-MS Homo sapiens 83 BAG2 9532 Affinity Capture-MS Homo sapiens 84 Gspt1 14852 Affinity Capture-MS Mus musculus 85 SIRT7   Affinity Capture-MS Homo sapiens 86 NCAPH2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 87 PCDHB15   Affinity Capture-MS Homo sapiens 88 FOXG1   Affinity Capture-MS Homo sapiens 89 EBNA1BP2 10969 Co-fractionation Homo sapiens 90 YY1 7528 Proximity Label-MS Homo sapiens 91 PNMA2   Affinity Capture-MS Homo sapiens 92 HIST3H3 8290 Protein-peptide Homo sapiens 93 HNRNPCL2 440563 Affinity Capture-MS Homo sapiens 94 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 95 HNF4A   Proximity Label-MS Homo sapiens 96 ABTB2 25841 Affinity Capture-MS Homo sapiens 97 C12orf74   Affinity Capture-MS Homo sapiens 98 MYC   Affinity Capture-MS Homo sapiens 99 RPA3 6119 Proximity Label-MS Homo sapiens 100 TOP1 7150 Affinity Capture-MS Homo sapiens 101 NUBP1 4682 Affinity Capture-MS Homo sapiens 102 RNF2   Affinity Capture-MS Homo sapiens 103 BMI1   Affinity Capture-MS Homo sapiens 104 FOXQ1   Affinity Capture-MS Homo sapiens 105 NFATC2   Affinity Capture-MS Homo sapiens 106 BRD3 8019 Affinity Capture-MS Homo sapiens 107 ZMYM2   Affinity Capture-MS Homo sapiens 108 CCDC8   Affinity Capture-MS Homo sapiens 109 EIF3D 8664 Affinity Capture-MS Homo sapiens 110 Cbx1   Affinity Capture-MS Mus musculus 111 CRYAA 1409 Affinity Capture-MS Homo sapiens 112 RBPJ 3516 Affinity Capture-MS Homo sapiens 113 ATRX 546 Affinity Capture-MS Homo sapiens 114 SIRT6   Affinity Capture-MS Homo sapiens 115 GRK6 2870 Affinity Capture-MS Homo sapiens 116 TP53 7157 Affinity Capture-MS Homo sapiens 117 RRS1 23212 Co-fractionation Homo sapiens 118 L3MBTL2   Affinity Capture-MS Homo sapiens 119 FOXJ2   Affinity Capture-MS Homo sapiens 120 CHAMP1   Affinity Capture-MS Homo sapiens 121 MEN1 4221 Affinity Capture-MS Homo sapiens 122 ADNP2   Affinity Capture-MS Homo sapiens 123 FOXE1   Affinity Capture-MS Homo sapiens 124 CDC27 996 Two-hybrid Homo sapiens 125 HDAC1 3065 Affinity Capture-MS Homo sapiens 126 CHD4 1108 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 127 ESR1   Affinity Capture-MS Homo sapiens 128 HDGFRP2 84717 Affinity Capture-MS Homo sapiens 129 KDM1A 23028 Proximity Label-MS Homo sapiens 130 PCGF6   Affinity Capture-MS Homo sapiens 131 CIT 11113 Affinity Capture-MS Homo sapiens 132 XRCC6 2547 Proximity Label-MS Homo sapiens 133 CHAF1B   Affinity Capture-MS Homo sapiens 134 SSRP1 6749 Affinity Capture-MS Homo sapiens 135 SAP18 10284 Co-fractionation Homo sapiens 136 CCT8L2   Affinity Capture-MS Homo sapiens 137 HSPA2 3306 Affinity Capture-MS Homo sapiens View the network

Pathways in which ADNP is involved

No pathways found