Gene description for OSBPL9
Gene name oxysterol binding protein-like 9
Gene symbol OSBPL9
Other names/aliases ORP-9
ORP9
Species Homo sapiens
 Database cross references - OSBPL9
ExoCarta ExoCarta_114883
Entrez Gene 114883
HGNC 16386
MIM 606737
UniProt Q96SU4  
 OSBPL9 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for OSBPL9
Molecular Function
    lipid binding GO:0008289 IEA
Biological Process
    lipid transport GO:0006869 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    cytoplasm GO:0005737 IDA
    late endosome membrane GO:0031902 IEA
 Experiment description of studies that identified OSBPL9 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for OSBPL9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OSBPL9 is involved
No pathways found





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