Gene description for BET1L
Gene name Bet1 golgi vesicular membrane trafficking protein-like
Gene symbol BET1L
Other names/aliases BET1L1
GOLIM3
GS15
HSPC197
Species Homo sapiens
 Database cross references - BET1L
ExoCarta ExoCarta_51272
Vesiclepedia VP_51272
Entrez Gene 51272
HGNC 19348
MIM 615417
UniProt Q9NYM9  
 BET1L identified in exosomes derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for BET1L
Molecular Function
    SNAP receptor activity GO:0005484 IDA
Biological Process
    retrograde transport, endosome to Golgi GO:0042147 IDA
    regulation of retrograde vesicle-mediated transport, Golgi to ER GO:2000156 IMP
    protein transport GO:0015031 IEA
    membrane fusion GO:0061025 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 IDA
    Golgi stack GO:0005795 IEA
    endosome GO:0005768 IDA
    SNARE complex GO:0031201 TAS
    membrane GO:0016020 IDA
    integral component of Golgi membrane GO:0030173 IEA
 Experiment description of studies that identified BET1L in exosomes
1
Experiment ID 834
MISEV standards
✔
EM
EV Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for BET1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STX5 6811
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 YKT6 10652
Affinity Capture-Western Homo sapiens
3 GOSR1 9527
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which BET1L is involved
No pathways found





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