Gene description for UBE3B
Gene name ubiquitin protein ligase E3B
Gene symbol UBE3B
Other names/aliases BPIDS
KOS
Species Homo sapiens
 Database cross references - UBE3B
ExoCarta ExoCarta_89910
Entrez Gene 89910
HGNC 13478
MIM 608047
UniProt Q7Z3V4  
 UBE3B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for UBE3B
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 IBA
    ligase activity GO:0016874 IEA
Biological Process
    protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified UBE3B in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBE3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which UBE3B is involved
PathwayEvidenceSource
Antigen processing: Ubiquitination & Proteasome degradation TAS Reactome





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