Gene description for UHRF1BP1L
Gene name UHRF1 binding protein 1-like
Gene symbol UHRF1BP1L
Other names/aliases SHIP164
Species Homo sapiens
 Database cross references - UHRF1BP1L
ExoCarta ExoCarta_23074
Vesiclepedia VP_23074
Entrez Gene 23074
HGNC 29102
UniProt A0JNW5  
 UHRF1BP1L identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for UHRF1BP1L
Molecular Function
    protein binding GO:0005515 IPI
    protein homodimerization activity GO:0042803 IPI
    GARP complex binding GO:0062069 IDA
    lipid transfer activity GO:0120013 IDA
Biological Process
    early endosome to Golgi transport GO:0034498 IDA
    intermembrane lipid transfer GO:0120009 IDA
Subcellular Localization
    early endosome GO:0005769 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified UHRF1BP1L in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UHRF1BP1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-MS Homo sapiens
2 RAB8B 51762
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 ATXN1 6310
Two-hybrid Homo sapiens
4 YWHAG 7532
Affinity Capture-MS Homo sapiens
5 RAC1 5879
Affinity Capture-MS Homo sapiens
6 RAB35 11021
Proximity Label-MS Homo sapiens
7 ANKFY1 51479
Proximity Label-MS Homo sapiens
8 DCXR 51181
Affinity Capture-MS Homo sapiens
9 OCLN 100506658
Proximity Label-MS Homo sapiens
10 LAMTOR1 55004
Proximity Label-MS Homo sapiens
11 MSRB2  
Affinity Capture-MS Homo sapiens
12 RAB5A 5868
Proximity Label-MS Homo sapiens
13 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 YWHAQ 10971
Affinity Capture-MS Homo sapiens
15 Rab5b 19344
Affinity Capture-MS Mus musculus
16 DOK3 79930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 RAB9A 9367
Proximity Label-MS Homo sapiens
18 SCML1  
Affinity Capture-MS Homo sapiens
19 MIF 4282
Affinity Capture-MS Homo sapiens
20 YWHAZ 7534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 IFFO1  
Affinity Capture-MS Homo sapiens
22 LAMP2 3920
Proximity Label-MS Homo sapiens
23 LOC254896  
Affinity Capture-MS Homo sapiens
24 COX8A  
Proximity Label-MS Homo sapiens
25 ATG9A 79065
Proximity Label-MS Homo sapiens
26 COBLL1 22837
Affinity Capture-MS Homo sapiens
27 AMOTL1 154810
Affinity Capture-MS Homo sapiens
28 RAB4A 5867
Proximity Label-MS Homo sapiens
29 RAB3B 5865
Proximity Label-MS Homo sapiens
30 CDK2 1017
Affinity Capture-MS Homo sapiens
31 RPA3 6119
Proximity Label-MS Homo sapiens
32 FERMT3 83706
Affinity Capture-MS Homo sapiens
33 YWHAE 7531
Affinity Capture-MS Homo sapiens
34 DIO3  
Affinity Capture-MS Homo sapiens
35 RASEF  
Affinity Capture-MS Homo sapiens
36 RAB11A 8766
Proximity Label-MS Homo sapiens
37 GOLGA1  
Proximity Label-MS Homo sapiens
38 CT55  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 FAM174A 345757
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 RAB2A 5862
Proximity Label-MS Homo sapiens
41 RAB5C 5878
Proximity Label-MS Homo sapiens
42 FNTB 2342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CHD8 57680
Affinity Capture-MS Homo sapiens
44 Dynll1 56455
Affinity Capture-MS Mus musculus
45 FBXO10  
Affinity Capture-MS Homo sapiens
46 BAGE2  
Affinity Capture-MS Homo sapiens
47 DYNLL2 140735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 DNMT1 1786
Affinity Capture-MS Homo sapiens
49 CDADC1  
Affinity Capture-MS Homo sapiens
50 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 STX6 10228
Proximity Label-MS Homo sapiens
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