Gene description for DOPEY2
Gene name dopey family member 2
Gene symbol DOPEY2
Other names/aliases 21orf5
C21orf5
Species Homo sapiens
 Database cross references - DOPEY2
ExoCarta ExoCarta_9980
Entrez Gene 9980
HGNC 1291
MIM 604803
UniProt Q9Y3R5  
 DOPEY2 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
Urine 19056867    
 Gene ontology annotations for DOPEY2
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    Golgi to endosome transport GO:0006895 ISS
    protein transport GO:0015031 IEA
    multicellular organismal development GO:0007275 NAS
    endoplasmic reticulum organization GO:0007029 ISS
    cognition GO:0050890 IMP
Subcellular Localization
    Golgi membrane GO:0000139 ISS
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified DOPEY2 in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
2
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for DOPEY2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DOPEY2 is involved
No pathways found





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