Gene description for ATG2B
Gene name autophagy related 2B
Gene symbol ATG2B
Other names/aliases C14orf103
Species Homo sapiens
 Database cross references - ATG2B
ExoCarta ExoCarta_55102
Vesiclepedia VP_55102
Entrez Gene 55102
HGNC 20187
MIM 616226
UniProt Q96BY7  
 ATG2B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ATG2B
Molecular Function
    protein binding GO:0005515 IPI
    phosphatidylinositol-3-phosphate binding GO:0032266 IBA
    protein-membrane adaptor activity GO:0043495 IBA
    lipid transfer activity GO:0120013 IDA
Biological Process
    autophagosome assembly GO:0000045 IBA
    autophagy of mitochondrion GO:0000422 IBA
    pexophagy GO:0000425 IBA
    piecemeal microautophagy of the nucleus GO:0034727 IBA
    reticulophagy GO:0061709 IBA
    glycophagy GO:0061723 IBA
    intermembrane lipid transfer GO:0120009 IEA
Subcellular Localization
    phagophore assembly site GO:0000407 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    lipid droplet GO:0005811 IEA
    phagophore assembly site membrane GO:0034045 IEA
    phagophore GO:0061908 IBA
 Experiment description of studies that identified ATG2B in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ATG2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRINP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 TACR3  
Affinity Capture-MS Homo sapiens
3 MAGEA8  
Affinity Capture-MS Homo sapiens
4 WDR45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 PHLPP1  
Proximity Label-MS Homo sapiens
6 CCDC96  
Affinity Capture-MS Homo sapiens
7 SALL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
9 MYCN  
Affinity Capture-MS Homo sapiens
10 NPAS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 LHX6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CUL3 8452
Affinity Capture-MS Homo sapiens
13 ATG5 9474
Proximity Label-MS Homo sapiens
14 DOCK5 80005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 USP15 9958
Affinity Capture-MS Homo sapiens
16 TALDO1 6888
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 MCM5 4174
Affinity Capture-MS Homo sapiens
18 RAB5A 5868
Proximity Label-MS Homo sapiens
19 PTH2R  
Affinity Capture-MS Homo sapiens
20 ATG2A  
Affinity Capture-MS Homo sapiens
21 EDEM1  
Affinity Capture-MS Homo sapiens
22 SKP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 DUSP26 78986
Affinity Capture-MS Homo sapiens
24 WIPI1 55062
Affinity Capture-MS Homo sapiens
25 TKT 7086
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 MCM4 4173
Affinity Capture-MS Homo sapiens
27 HDAC11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 SNX21  
Affinity Capture-MS Homo sapiens
29 SLAMF1 6504
Affinity Capture-MS Homo sapiens
30 LINC00346  
Affinity Capture-MS Homo sapiens
31 AP1G2 8906
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 RAB4A 5867
Proximity Label-MS Homo sapiens
33 MLF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 C6orf141  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 RPA3 6119
Proximity Label-MS Homo sapiens
36 ABTB2 25841
Affinity Capture-MS Homo sapiens
37 SENP3 26168
Affinity Capture-MS Homo sapiens
38 ARHGAP36  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 NTRK1 4914
Affinity Capture-MS Homo sapiens
40 MCM2 4171
Affinity Capture-MS Homo sapiens
41 RAB7A 7879
Proximity Label-MS Homo sapiens
42 GOLGA1  
Proximity Label-MS Homo sapiens
43 ZSCAN26  
Affinity Capture-MS Homo sapiens
44 SPAG9 9043
Affinity Capture-MS Homo sapiens
45 IMPDH2 3615
Proximity Label-MS Homo sapiens
46 RPA4  
Proximity Label-MS Homo sapiens
47 RAB5C 5878
Proximity Label-MS Homo sapiens
48 ZFYVE1 53349
Affinity Capture-MS Homo sapiens
49 HAX1  
Proximity Label-MS Homo sapiens
50 DUSP16  
Affinity Capture-MS Homo sapiens
51 MCM6 4175
Affinity Capture-MS Homo sapiens
52 ARSK  
Affinity Capture-MS Homo sapiens
53 DEF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 NLRP10  
Affinity Capture-MS Homo sapiens
55 AKAP1 8165
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ATG2B is involved
No pathways found





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