Gene ontology annotations for SLC19A1
Experiment description of studies that identified SLC19A1 in sEVs
1
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34887515
Organism
Homo sapiens
Experiment description
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors
"Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Colorectal cancer cells
Sample name
DiFi
Isolation/purification methods
Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein miRNA
Methods used in the study
Western blotting Mass spectrometry RNA sequencing
5
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SLC19A1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ATP2B3
492
Affinity Capture-MS
Homo sapiens
2
CD164L2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
GJD3
Proximity Label-MS
Homo sapiens
4
RAB35
11021
Proximity Label-MS
Homo sapiens
5
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
6
ANKFY1
51479
Proximity Label-MS
Homo sapiens
7
NHLRC3
387921
Affinity Capture-MS
Homo sapiens
8
OCLN
100506658
Proximity Label-MS
Homo sapiens
9
CANX
821
Affinity Capture-MS
Homo sapiens
10
LAMTOR1
55004
Proximity Label-MS
Homo sapiens
11
MARCKS
4082
Proximity Label-MS
Homo sapiens
12
LAMP3
Proximity Label-MS
Homo sapiens
13
RAB5A
5868
Proximity Label-MS
Homo sapiens
14
LMAN1
3998
Proximity Label-MS
Homo sapiens
15
HCST
Affinity Capture-MS
Homo sapiens
16
ATG9A
79065
Affinity Capture-MS
Homo sapiens
17
EPB41L4A
64097
Proximity Label-MS
Homo sapiens
18
LAMP1
3916
Proximity Label-MS
Homo sapiens
19
VAMP3
9341
Affinity Capture-MS
Homo sapiens
20
GJA1
2697
Proximity Label-MS
Homo sapiens
21
LAMP2
3920
Proximity Label-MS
Homo sapiens
22
ARF6
382
Proximity Label-MS
Homo sapiens
23
ERGIC1
57222
Proximity Label-MS
Homo sapiens
24
C11orf52
91894
Proximity Label-MS
Homo sapiens
25
KRT26
353288
Two-hybrid
Homo sapiens
26
LYN
4067
Proximity Label-MS
Homo sapiens
27
RAB4A
5867
Proximity Label-MS
Homo sapiens
28
DNAJC5
80331
Proximity Label-MS
Homo sapiens
29
B3GAT1
Proximity Label-MS
Homo sapiens
30
RAB2A
5862
Proximity Label-MS
Homo sapiens
31
MLLT4
4301
Proximity Label-MS
Homo sapiens
32
DIRAS3
Proximity Label-MS
Homo sapiens
33
RAB9A
9367
Proximity Label-MS
Homo sapiens
34
APOB
338
Affinity Capture-MS
Homo sapiens
35
TNFRSF10C
Affinity Capture-MS
Homo sapiens
36
KRAS
3845
Proximity Label-MS
Homo sapiens
37
RAB5C
5878
Proximity Label-MS
Homo sapiens
38
RHOB
388
Proximity Label-MS
Homo sapiens
39
STX4
6810
Proximity Label-MS
Homo sapiens
40
CAV1
857
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
41
ATP2A3
489
Affinity Capture-MS
Homo sapiens
42
FLOT1
10211
Proximity Label-MS
Homo sapiens
43
STX6
10228
Proximity Label-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which SLC19A1 is involved