Gene description for HTATIP2
Gene name HIV-1 Tat interactive protein 2, 30kDa
Gene symbol HTATIP2
Other names/aliases CC3
SDR44U1
TIP30
Species Homo sapiens
 Database cross references - HTATIP2
ExoCarta ExoCarta_10553
Entrez Gene 10553
HGNC 16637
MIM 605628
UniProt Q9BUP3  
 HTATIP2 identified in exosomes derived from the following tissue/cell type
Breast cancer cells 19415654    
Thymus 23844026    
 Gene ontology annotations for HTATIP2
Molecular Function
    protein binding GO:0005515 IPI
    oxidoreductase activity GO:0016491 IEA
    transcription coactivator activity GO:0003713 TAS
Biological Process
    apoptotic process GO:0006915 IEA
    negative regulation of apoptotic process GO:0043066 TAS
    regulation of angiogenesis GO:0045765 IDA
    cell differentiation GO:0030154 IEA
    oxidation-reduction process GO:0055114 IEA
    viral process GO:0016032 IEA
    regulation of transcription from RNA polymerase II promoter GO:0006357 TAS
    angiogenesis GO:0001525 IEA
    nuclear import GO:0051170 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IDA
    nucleus GO:0005634 TAS
    nuclear envelope GO:0005635 IDA
 Experiment description of studies that identified HTATIP2 in exosomes
1
Experiment ID 65
ISEV standards
EV Biophysical techniques
HSP60|HSP27|GAPDH
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors Staubach S, Razawi H, Hanisch FG.
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
2
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HTATIP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HTATIP2 is involved
No pathways found





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