Gene description for WDR7
Gene name WD repeat domain 7
Gene symbol WDR7
Other names/aliases TRAG
Species Homo sapiens
 Database cross references - WDR7
ExoCarta ExoCarta_23335
Vesiclepedia VP_23335
Entrez Gene 23335
HGNC 13490
MIM 613473
UniProt Q9Y4E6  
 WDR7 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for WDR7
Biological Process
    hematopoietic progenitor cell differentiation GO:0002244 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified WDR7 in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WDR7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
2 DMXL2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
3 UGGT2 55757
Affinity Capture-MS Homo sapiens
4 ROGDI 79641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 MECP2 4204
Affinity Capture-MS Homo sapiens
6 RAB35 11021
Proximity Label-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 DENND6A 201627
Proximity Label-MS Homo sapiens
9 METTL7A 25840
Proximity Label-MS Homo sapiens
10 LAMTOR1 55004
Proximity Label-MS Homo sapiens
11 ATP6V1B2 526
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 RAB5A 5868
Proximity Label-MS Homo sapiens
13 RAB9A 9367
Proximity Label-MS Homo sapiens
14 DDOST 1650
Affinity Capture-MS Homo sapiens
15 ARF3 377
Proximity Label-MS Homo sapiens
16 DMXL1 1657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 BNIP1 662
Affinity Capture-MS Homo sapiens
18 LAMP2 3920
Proximity Label-MS Homo sapiens
19 VHL  
Negative Genetic Homo sapiens
20 ATP6V1G2  
Affinity Capture-MS Homo sapiens
21 CXADR 1525
Proximity Label-MS Homo sapiens
22 ATP6V1F 9296
Affinity Capture-MS Homo sapiens
23 RAB4A 5867
Proximity Label-MS Homo sapiens
24 MYC  
Affinity Capture-MS Homo sapiens
25 ATP6V1G1 9550
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 NTRK1 4914
Affinity Capture-MS Homo sapiens
27 EGFR 1956
Negative Genetic Homo sapiens
28 RAB11A 8766
Proximity Label-MS Homo sapiens
29 SSSCA1 10534
Affinity Capture-MS Homo sapiens
30 RAB3B 5865
Proximity Label-MS Homo sapiens
31 RAB7A 7879
Proximity Label-MS Homo sapiens
32 RPN1 6184
Affinity Capture-MS Homo sapiens
33 RAB3GAP1 22930
Affinity Capture-Western Homo sapiens
34 KRAS 3845
Negative Genetic Homo sapiens
35 RAB5C 5878
Proximity Label-MS Homo sapiens
36 ATG9A 79065
Proximity Label-MS Homo sapiens
37 ATP6V1B1 525
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 ATP6V1E1 529
Affinity Capture-MS Homo sapiens
39 FRMD6 122786
Two-hybrid Homo sapiens
40 STX6 10228
Proximity Label-MS Homo sapiens
41 OST4  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which WDR7 is involved
No pathways found





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