|
 Gene description for COL21A1 |
| Gene name |
collagen, type XXI, alpha 1 |
| Gene symbol |
COL21A1 |
| Other names/aliases |
COLA1L
FP633
dJ682J15.1
dJ708F5.1 |
| Species |
Homo sapiens |
| Database cross references - COL21A1 |
| ExoCarta |
ExoCarta_81578 |
| Entrez Gene |
81578 |
| HGNC |
17025 |
| MIM |
610002 |
| UniProt |
Q96P44
|
| COL21A1 identified in exosomes derived from the following tissue/cell type |
|
Hepatocytes
|
26054723
|
|
Urine
|
21595033
|
|
Urine
|
21595033
|
|
Urine
|
21595033
|
| Gene ontology annotations for COL21A1 |
|
|
| Experiment description of studies that identified COL21A1 in exosomes |
| 1 |
| Experiment ID |
237 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
TSG101|Alix|HSC70|GAPDH
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✔
HSP90B1
|
EV Negative markers |
|
✔
qNano
|
EV Particle analysis
|
|
| Identified molecule |
mRNA
|
| Identification method |
RNA Sequencing
|
| PubMed ID |
26054723
|
| Organism |
Homo sapiens |
| Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
| Authors |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N |
| Journal name |
Carcinogenesis
|
| Publication year |
2015 |
| Sample |
Hepatocytes |
| Sample name |
MIHA |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.13-1.19 g/mL
|
| Molecules identified in the study |
Protein
RNA |
| Methods used in the study |
Western blotting
Mass spectrometry
RNA Sequencing |
|
|
| 2 |
| Experiment ID |
193 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✔
CD63|CD9
|
EV Membrane markers |
|
✔
PHB
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
21595033
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
| Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
| Journal name |
Proteomics
|
| Publication year |
2011 |
| Sample |
Urine |
| Sample name |
Urine - Normal |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 3 |
| Experiment ID |
194 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
21595033
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
| Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
| Journal name |
Proteomics
|
| Publication year |
2011 |
| Sample |
Urine |
| Sample name |
Urine - Patients of basement membrane nephropathy |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 4 |
| Experiment ID |
195 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✘
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
21595033
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
| Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
| Journal name |
Proteomics
|
| Publication year |
2011 |
| Sample |
Urine |
| Sample name |
Urine - Patients of early IgA nephropathy |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| Protein-protein interactions for COL21A1 |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which COL21A1 is involved |
|
|
|
