Gene description for COL2A1
Gene name	collagen, type II, alpha 1
Gene symbol	COL2A1
Other names/aliases	ANFH AOM COL11A3 SEDC STL1
Species	Homo sapiens
Database cross references - COL2A1
ExoCarta	ExoCarta_1280
Entrez Gene	1280
HGNC	2200
MIM	120140
UniProt	P02458
COL2A1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for COL2A1

Molecular Function     metal ion binding GO:0046872 IEA     identical protein binding GO:0042802 NAS     platelet-derived growth factor binding GO:0048407 IDA     extracellular matrix structural constituent conferring tensile strength GO:0030020 IC Biological Process     cartilage condensation GO:0001502 IEA     collagen catabolic process GO:0030574 TAS     tissue homeostasis GO:0001894 IEA     central nervous system development GO:0007417 IEA     limb bud formation GO:0060174 IEA     regulation of gene expression GO:0010468 IEA     cartilage development involved in endochondral bone morphogenesis GO:0060351 IEA     proteoglycan metabolic process GO:0006029 IEA     endochondral ossification GO:0001958 IEA     otic vesicle development GO:0071599 IEA     negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 IEA     palate development GO:0060021 IEA     extracellular matrix disassembly GO:0022617 TAS     inner ear morphogenesis GO:0042472 IEA     skeletal system development GO:0001501 IMP     embryonic skeletal joint morphogenesis GO:0060272 IMP     visual perception GO:0007601 IMP     cellular response to BMP stimulus GO:0071773 IEA     cartilage development GO:0051216 TAS     extracellular matrix organization GO:0030198 TAS     sensory perception of sound GO:0007605 IMP     heart morphogenesis GO:0003007 IEA     notochord development GO:0030903 IEA     axon guidance GO:0007411 TAS     collagen fibril organization GO:0030199 IMP     chondrocyte differentiation GO:0002062 IEA Subcellular Localization     basement membrane GO:0005604 IEA     extracellular space GO:0005615 IEA     extracellular region GO:0005576 TAS     collagen type II trimer GO:0005585 IDA     endoplasmic reticulum lumen GO:0005788 TAS     extracellular matrix GO:0031012 IDA