Gene description for DVL1
Gene name	dishevelled segment polarity protein 1
Gene symbol	DVL1
Other names/aliases	DRS2 DVL DVL1L1 DVL1P1
Species	Homo sapiens
Database cross references - DVL1
ExoCarta	ExoCarta_1855
Vesiclepedia	VP_1855
Entrez Gene	1855
HGNC	3084
MIM	601365
UniProt	O14640
DVL1 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for DVL1

Molecular Function     frizzled binding GO:0005109 IBA     frizzled binding GO:0005109 IPI     frizzled binding GO:0005109 TAS     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 IEA     enzyme binding GO:0019899 IPI     protein kinase binding GO:0019901 IPI     small GTPase binding GO:0031267 IEA     identical protein binding GO:0042802 IPI Biological Process     heart looping GO:0001947 ISS     outflow tract morphogenesis GO:0003151 ISS     regulation of DNA-templated transcription GO:0006355 IDA     neurotransmitter secretion GO:0007269 ISS     axon guidance GO:0007411 IEA     neuromuscular junction development GO:0007528 ISS     positive regulation of neuron projection development GO:0010976 IEA     synaptic vesicle exocytosis GO:0016079 IEA     neural tube development GO:0021915 IEP     convergent extension involved in neural plate elongation GO:0022007 IEA     cytoplasmic microtubule organization GO:0031122 IEA     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IMP     regulation of protein localization GO:0032880 IDA     protein localization to nucleus GO:0034504 IMP     social behavior GO:0035176 IEA     protein localization to microtubule GO:0035372 IEA     intracellular signal transduction GO:0035556 IEA     non-canonical Wnt signaling pathway GO:0035567 TAS     receptor clustering GO:0043113 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     collateral sprouting GO:0048668 IEA     axon extension GO:0048675 IEA     dendrite morphogenesis GO:0048813 ISS     synapse organization GO:0050808 ISS     protein stabilization GO:0050821 IDA     canonical Wnt signaling pathway GO:0060070 IBA     canonical Wnt signaling pathway GO:0060070 IDA     canonical Wnt signaling pathway GO:0060070 IGI     canonical Wnt signaling pathway GO:0060070 TAS     Wnt signaling pathway, planar cell polarity pathway GO:0060071 IDA     Wnt signaling pathway, planar cell polarity pathway GO:0060071 NAS     prepulse inhibition GO:0060134 IEA     dendritic spine morphogenesis GO:0060997 IEA     skeletal muscle acetylcholine-gated channel clustering GO:0071340 IEA     cochlea morphogenesis GO:0090103 IEA     presynapse assembly GO:0099054 TAS     regulation of postsynapse organization GO:0099175 IEA     positive regulation of neuron projection arborization GO:0150012 ISS     positive regulation of protein localization to presynapse GO:1905386 TAS     regulation of synaptic vesicle exocytosis GO:2000300 IEA     positive regulation of excitatory postsynaptic potential GO:2000463 IEA Subcellular Localization     cytosol GO:0005829 IBA     cytosol GO:0005829 TAS     microtubule GO:0005874 IEA     postsynaptic density GO:0014069 IEA     lateral plasma membrane GO:0016328 IDA     clathrin-coated vesicle GO:0030136 IEA     growth cone GO:0030426 IDA     cytoplasmic vesicle GO:0031410 IDA     cytoplasmic vesicle GO:0031410 ISS     neuron projection GO:0043005 IDA     neuronal cell body GO:0043025 IEA     dendritic spine GO:0043197 IEA     synapse GO:0045202 ISS     Schaffer collateral - CA1 synapse GO:0098685 IEA     presynapse GO:0098793 IEA     glutamatergic synapse GO:0098978 IEA     neuronal dense core vesicle GO:0098992 IEA     Wnt signalosome GO:1990909 IEA