Gene description for DVL1
Gene name	dishevelled segment polarity protein 1
Gene symbol	DVL1
Other names/aliases	DRS2 DVL DVL1L1 DVL1P1
Species	Homo sapiens
Database cross references - DVL1
ExoCarta	ExoCarta_1855
Entrez Gene	1855
HGNC	3084
MIM	601365
UniProt	O14640
DVL1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for DVL1

Molecular Function     frizzled binding GO:0005109 IPI     molecular_function GO:0003674 ND     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IPI     protein kinase binding GO:0019901 IPI     enzyme binding GO:0019899 IPI     Rac GTPase binding GO:0048365 IEA Biological Process     skeletal muscle acetylcholine-gated channel clustering GO:0071340 IEA     protein localization to nucleus GO:0034504 IMP     neurotransmitter secretion GO:0007269 ISS     negative regulation of canonical Wnt signaling pathway GO:0090090 TAS     axon extension GO:0048675 IEA     canonical Wnt signaling pathway GO:0060070 IDA     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IMP     convergent extension involved in neural plate elongation GO:0022007 IEA     collateral sprouting GO:0048668 IEA     neuromuscular junction development GO:0007528 ISS     Wnt signaling pathway, planar cell polarity pathway GO:0060071 IDA     positive regulation of Wnt signaling pathway GO:0030177 IDA     positive regulation of transcription, DNA-templated GO:0045893 IDA     neural tube development GO:0021915 IEP     prepulse inhibition GO:0060134 IEA     Wnt signaling pathway GO:0016055 IEA     negative regulation of protein binding GO:0032091 IDA     positive regulation of canonical Wnt signaling pathway GO:0090263 TAS     synapse organization GO:0050808 ISS     axon guidance GO:0007411 IEA     social behavior GO:0035176 IEA     receptor clustering GO:0043113 ISS     protein localization to microtubule GO:0035372 IEA     heart development GO:0007507 NAS     cytoplasmic microtubule organization GO:0031122 IEA     dendrite morphogenesis GO:0048813 ISS     regulation of neurotransmitter levels GO:0001505 ISS     negative regulation of protein kinase activity GO:0006469 IDA     cochlea morphogenesis GO:0090103 IEA     planar cell polarity pathway involved in neural tube closure GO:0090179 IBA     transcription from RNA polymerase II promoter GO:0006366 IDA     positive regulation of neuron projection development GO:0010976 IEA     intracellular signal transduction GO:0035556 IEA Subcellular Localization     cytoplasm GO:0005737 IEA     neuronal cell body GO:0043025 IEA     cytosol GO:0005829 TAS     dendrite GO:0030425 IEA     axon GO:0030424 IEA     microtubule GO:0005874 IEA     clathrin-coated vesicle GO:0030136 IEA     cytoplasmic membrane-bounded vesicle GO:0016023 ISS     cytoplasmic vesicle GO:0031410 IDA     lateral plasma membrane GO:0016328 IDA     synapse GO:0045202 ISS     growth cone GO:0030426 IEA