Gene description for WWTR1
Gene name	WW domain containing transcription regulator 1
Gene symbol	WWTR1
Other names/aliases	TAZ
Species	Homo sapiens
Database cross references - WWTR1
ExoCarta	ExoCarta_25937
Vesiclepedia	VP_25937
Entrez Gene	25937
HGNC	24042
MIM	607392
UniProt	Q9GZV5
WWTR1 identified in exosomes derived from the following tissue/cell type
Endothelial cells	26027894
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for WWTR1

Molecular Function     transcription coregulator activity GO:0003712 IDA     transcription coactivator activity GO:0003713 IBA     transcription coactivator activity GO:0003713 IDA     transcription coactivator activity GO:0003713 IMP     transcription coactivator activity GO:0003713 NAS     transcription corepressor activity GO:0003714 IBA     protein binding GO:0005515 IPI     protein homodimerization activity GO:0042803 IEA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IEA     osteoblast differentiation GO:0001649 IEA     tissue homeostasis GO:0001894 IEA     negative regulation of protein phosphorylation GO:0001933 IMP     heart process GO:0003015 IEA     regulation of DNA-templated transcription GO:0006355 NAS     negative regulation of protein kinase activity GO:0006469 IMP     positive regulation of cell population proliferation GO:0008284 IDA     positive regulation of epithelial to mesenchymal transition GO:0010718 IDA     protein ubiquitination GO:0016567 IEA     stem cell division GO:0017145 IDA     SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146 IEA     glomerulus development GO:0032835 IEA     multicellular organism growth GO:0035264 IEA     hippo signaling GO:0035329 IBA     hippo signaling GO:0035329 IDA     negative regulation of fat cell differentiation GO:0045599 IGI     positive regulation of osteoblast differentiation GO:0045669 IGI     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     mesenchymal cell differentiation GO:0048762 IEA     cilium assembly GO:0060271 IEA     SMAD protein signal transduction GO:0060395 IDA     kidney morphogenesis GO:0060993 IEA     regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 IEA     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     positive regulation of protein localization to nucleus GO:1900182 ISS Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 IDA     nucleus GO:0005634 NAS     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     transcription regulator complex GO:0005667 IEA     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IEA     bicellular tight junction GO:0005923 IEA     nuclear body GO:0016604 IDA