Gene description for SETD4
Gene name SET domain containing 4
Gene symbol SETD4
Other names/aliases C21orf18
C21orf27
Species Homo sapiens
 Database cross references - SETD4
ExoCarta ExoCarta_54093
Entrez Gene 54093
HGNC 1258
UniProt Q9NVD3  
 SETD4 identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 19837982    
 Gene ontology annotations for SETD4
Molecular Function
    methyltransferase activity GO:0008168 IEA
Biological Process
    methylation GO:0032259 IEA
 Experiment description of studies that identified SETD4 in exosomes
1
Experiment ID 21
ISEV standards
EM|IEM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for SETD4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SETD4 is involved
No pathways found





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