Gene description for ZMIZ1
Gene name zinc finger, MIZ-type containing 1
Gene symbol ZMIZ1
Other names/aliases MIZ
RAI17
TRAFIP10
ZIMP10
hZIMP10
Species Homo sapiens
 Database cross references - ZMIZ1
ExoCarta ExoCarta_57178
Entrez Gene 57178
HGNC 16493
MIM 607159
UniProt Q9ULJ6  
 ZMIZ1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ZMIZ1
Molecular Function
    zinc ion binding GO:0008270 IEA
Biological Process
    cell aging GO:0007569 IEA
    transcription, DNA-templated GO:0006351 IEA
    developmental growth GO:0048589 IEA
    in utero embryonic development GO:0001701 IEA
    heart morphogenesis GO:0003007 IEA
    vasculogenesis GO:0001570 IEA
    vitellogenesis GO:0007296 IEA
    artery morphogenesis GO:0048844 IEA
    positive regulation of fibroblast proliferation GO:0048146 IEA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
Subcellular Localization
    nuclear speck GO:0016607 IEA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified ZMIZ1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZMIZ1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AR 367
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which ZMIZ1 is involved
No pathways found





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