Experiment description of studies that identified RAPGEF6 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM EV Biophysical techniques ✔ Alix|TSG101|CD63|CD81 EV Enriched markers ✔ GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for RAPGEF6

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MRAS 22808 Invivo Homo sapiens Invitro Homo sapiens 2 PTPN13 5783 Invitro Homo sapiens Two-hybrid Homo sapiens 3 GTP   Invitro Homo sapiens 4 RAP1A 5906 Invivo Homo sapiens Invitro Homo sapiens 5 RAP2A 5911 Invivo Homo sapiens Invitro Homo sapiens View the network

Pathways in which RAPGEF6 is involved

No pathways found