Gene description for MC1R
Gene name	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
Gene symbol	MC1R
Other names/aliases	CMM5 MSH-R SHEP2
Species	Homo sapiens
Database cross references - MC1R
ExoCarta	ExoCarta_4157
Entrez Gene	4157
HGNC	6929
MIM	155555
UniProt	Q01726
MC1R identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for MC1R

Molecular Function     protein binding GO:0005515 IPI     melanocortin receptor activity GO:0004977 TAS     melanocyte-stimulating hormone receptor activity GO:0004980 IPI     hormone binding GO:0042562 IEA     G-protein coupled peptide receptor activity GO:0008528 TAS     ubiquitin protein ligase binding GO:0031625 IPI Biological Process     positive regulation of protein kinase B signaling GO:0051897 ISS     positive regulation of protein kinase C signaling GO:0090037 ISS     positive regulation of protein kinase A signaling GO:0010739 ISS     negative regulation of tumor necrosis factor production GO:0032720 IMP     positive regulation of feeding behavior GO:2000253 IEA     multicellular organismal development GO:0007275 TAS     pigmentation GO:0043473 TAS     sensory perception of pain GO:0019233 IEA     melanin biosynthetic process GO:0042438 IEA     UV-damage excision repair GO:0070914 IDA     G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 TAS     intracellular signal transduction GO:0035556 ISS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS     UV protection GO:0009650 TAS     positive regulation of cAMP biosynthetic process GO:0030819 IDA Subcellular Localization     intracellular GO:0005622 ISS     plasma membrane GO:0005886 TAS     integral component of plasma membrane GO:0005887 TAS