Gene description for CCDC57
Gene name coiled-coil domain containing 57
Gene symbol CCDC57
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC57
ExoCarta ExoCarta_284001
Entrez Gene 284001
HGNC 27564
UniProt Q2TAC2  
 CCDC57 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CCDC57
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified CCDC57 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CCDC57
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CCDC57 is involved
No pathways found





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