Gene description for NUP160
Gene name nucleoporin 160kDa
Gene symbol NUP160
Other names/aliases -
Species Homo sapiens
 Database cross references - NUP160
ExoCarta ExoCarta_23279
Entrez Gene 23279
HGNC 18017
MIM 607614
UniProt Q12769  
 NUP160 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NUP160
Molecular Function
    nucleocytoplasmic transporter activity GO:0005487 IDA
    protein binding GO:0005515 IPI
Biological Process
    cytokine-mediated signaling pathway GO:0019221 TAS
    viral transcription GO:0019083 TAS
    cellular response to heat GO:0034605 TAS
    transmembrane transport GO:0055085 TAS
    mitotic nuclear envelope disassembly GO:0007077 TAS
    small molecule metabolic process GO:0044281 TAS
    post-translational protein modification GO:0043687 TAS
    regulation of cellular response to heat GO:1900034 TAS
    viral life cycle GO:0019058 TAS
    mitotic cell cycle GO:0000278 TAS
    glucose transport GO:0015758 TAS
    protein sumoylation GO:0016925 TAS
    small GTPase mediated signal transduction GO:0007264 TAS
    viral process GO:0016032 TAS
    regulation of glucose transport GO:0010827 TAS
    carbohydrate metabolic process GO:0005975 TAS
    mRNA export from nucleus GO:0006406 IDA
    protein transport GO:0015031 IEA
    cellular protein metabolic process GO:0044267 TAS
    gene expression GO:0010467 TAS
    hexose transport GO:0008645 TAS
Subcellular Localization
    nuclear pore GO:0005643 IDA
    cytosol GO:0005829 TAS
    nuclear pore outer ring GO:0031080 NAS
    nuclear envelope GO:0005635 TAS
    kinetochore GO:0000776 IDA
 Experiment description of studies that identified NUP160 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUP160
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAGED1  
Affinity Capture-MS Homo sapiens
2 SEC13 6396
Affinity Capture-Western Homo sapiens
3 NUP107  
Affinity Capture-Western Homo sapiens
4 NUP43 348995
Affinity Capture-Western Homo sapiens
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